Zinc finger protein 674

ZNF674
Identifiers
Aliases	ZNF674, MRX92, ZNF673B, zinc finger protein 674
External IDs	HomoloGene: 87837 GeneCards: ZNF674
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.3 Start 46,497,727 bp[1] End 46,545,457 bp[1]
Gene ontology Molecular function • DNA binding • metal ion binding • nucleic acid binding • RNA polymerase II transcription factor activity, sequence-specific DNA binding Cellular component • intracellular • cell nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • regulation of transcription from RNA polymerase II promoter • negative regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	641339	n/a
Ensembl	ENSG00000251192	n/a
UniProt	Q2M3X9	n/a
RefSeq (mRNA)	NM_001039891 NM_001146291 NM_001190417	n/a
RefSeq (protein)	NP_001034980 NP_001139763 NP_001177346	n/a
Location (UCSC)	Chr X: 46.5 – 46.55 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Zinc finger protein 674 is a protein that in humans is encoded by the ZNF674 gene. ^[3]

Function

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.