ZKSCAN5

ZKSCAN5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesZKSCAN5, ZFP95, ZNF914, ZSCAN37, ZFP-95, zinc finger with KRAB and SCAN domains 5
External IDsMGI: 107533 HomoloGene: 8734 GeneCards: ZKSCAN5
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q22.1Start99,504,651 bp[1]
End99,534,700 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23660

22757

Ensembl

ENSG00000196652

ENSMUSG00000055991

UniProt

Q9Y2L8

Q9Z1D8

RefSeq (mRNA)

NM_014569
NM_145102
NM_001318082
NM_001318083
NM_001318084

RefSeq (protein)

NP_001305011
NP_001305012
NP_001305013
NP_055384
NP_659570

Location (UCSC)Chr 7: 99.5 – 99.53 MbChr 5: 145.2 – 145.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein with KRAB and SCAN domains 5 is a protein that in humans is encoded by the ZKSCAN5 gene.[5][6]

This gene encodes a zinc finger protein of the Krüppel family. The protein contains a SCAN box and a KRAB A domain. A similar protein in mouse is differentially expressed in spermatogenesis. Two alternatively spliced transcript variants differing only in the five prime untranslated region (5' UTR) have been described. Additional variants have been found, but their full-length sequences have not been determined.[6]


References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000196652 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055991 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Dreyer SD, Zheng Q, Zabel B, Winterpacht A, Lee B (Feb 2000). "Isolation, characterization, and mapping of a zinc finger gene, ZFP95, containing both a SCAN box and an alternatively spliced KRAB A domain". Genomics. 62 (1): 119–22. doi:10.1006/geno.1999.5981. PMID 10585779.
  6. 1 2 "Entrez Gene: ZKSCAN5 zinc finger with KRAB and SCAN domains 5".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Thompson EE, Kuttab-Boulos H, Yang L, et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
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