XTP3-transactivated gene A protein

DCTPP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2A3Q, 2OIE, 2OIG, 2Q4P
Identifiers
Aliases	DCTPP1, RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
External IDs	MGI: 1913672 HomoloGene: 11329 GeneCards: DCTPP1
Gene location (Human)
Chr.	Chromosome 16 (human)[1]
End	30,430,075 bp[1]
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[2]
End	127,260,709 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• nucleotide binding; • pyrophosphatase activity; • protein binding; • hydrolase activity; • magnesium ion binding; • metal ion binding; • identical protein binding; • pyrimidine deoxyribonucleotide binding; • dCTP diphosphatase activity; • nucleoside-triphosphate diphosphatase activity;
Cellular component	• cytoplasm; • cytosol; • cell nucleus; • mitochondrion;
Biological process	• protein homotetramerization; • dCTP catabolic process; • nucleoside triphosphate catabolic process; • DNA protection; • dTTP catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	79077
	66422
	ENSG00000179958
	ENSMUSG00000042462
	Q9H773
	Q9QY93
	NM_024096
	NM_023203
	NP_077001
	NP_075692
	Wikidata
View/Edit Human	View/Edit Mouse

dCTP pyrophosphatase 1 is an enzyme that in humans is encoded by the DCTPP1 gene.^[5]^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000179958 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042462 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Moroz OV, Murzin AG, Makarova KS, Koonin EV, Wilson KS, Galperin MY (Mar 2005). "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions". J Mol Biol. 347 (2): 243–55. doi:10.1016/j.jmb.2005.01.030. PMID 15740738.
↑ "Entrez Gene: XTP3TPA XTP3-transactivated protein A".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

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