Voltage-gated potassium-channel Kv1.4 IRES

Voltage-gated potassium-channel Kv1.4 IRES
Predicted secondary structure and sequence conservation of IRES_Kv1_4
Identifiers
Symbol IRES_Kv1_4
Rfam RF00447
Other data
RNA type Cis-reg; IRES
Domain(s) Eukaryota
GO 0043022
SO 0000243
PDB structures PDBe

This family represents the Kv1.4 voltage-gated potassium channel internal ribosome entry site (IRES). This region has been shown to mediate internal ribosome entry in cells derived from brain, heart, and skeletal muscle; tissues known to express Kv1.4 mRNA species.[1]

References

  1. Jang, GM; Leong LE; Hoang LT; Wang PH; Gutman GA; Semler BL (2004). "Structurally distinct elements mediate internal ribosome entry within the 5'-noncoding region of a voltage-gated potassium channel mRNA". J Biol Chem. 279 (46): 47419&ndash, 47430. doi:10.1074/jbc.M405885200. PMID 15339906.
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