VSX2

VSX2
Identifiers
AliasesVSX2, CHX10, HOX10, MCOP2, MCOPCB3, RET1, visual system homeobox 2
External IDsMGI: 88401 HomoloGene: 7266 GeneCards: VSX2
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q24.3Start74,239,472 bp[1]
End74,262,738 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

338917

12677

Ensembl

ENSG00000119614

ENSMUSG00000021239

UniProt

P58304

Q61412

RefSeq (mRNA)

NM_182894

NM_001301427
NM_007701

RefSeq (protein)

NP_878314

NP_001288356
NP_031727

Location (UCSC)Chr 14: 74.24 – 74.26 MbChr 12: 84.57 – 84.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000119614 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021239 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
  6. ↑ "Entrez Gene: CHX10 ceh-10 homeodomain containing homolog (C. elegans)".

Further reading

  • "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
  • Ferda Percin E, Ploder LA, Yu JJ, et al. (2000). "Human microphthalmia associated with mutations in the retinal homeobox gene CHX10". Nat. Genet. 25 (4): 397–401. doi:10.1038/78071. PMID 10932181.
  • Mikkola I, Bruun JA, Holm T, Johansen T (2001). "Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins". J. Biol. Chem. 276 (6): 4109–18. doi:10.1074/jbc.M008882200. PMID 11069920.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
  • Bar-Yosef U, Abuelaish I, Harel T, et al. (2005). "CHX10 mutations cause non-syndromic microphthalmia/ anophthalmia in Arab and Jewish kindreds". Hum. Genet. 115 (4): 302–9. doi:10.1007/s00439-004-1154-2. PMID 15257456.
  • Dorval KM, Bobechko BP, Ahmad KF, Bremner R (2005). "Transcriptional activity of the paired-like homeodomain proteins CHX10 and VSX1". J. Biol. Chem. 280 (11): 10100–8. doi:10.1074/jbc.M412676200. PMID 15647262.
  • Kuiper H, Spötter A, Williams JL, et al. (2005). "Physical mapping of CHX10, ALDH6A1, and ABCD4 on bovine chromosome 10q34". Cytogenet. Genome Res. 109 (4): 533. doi:10.1159/000084217. PMID 15909363.
  • Dorval KM, Bobechko BP, Fujieda H, et al. (2006). "CHX10 targets a subset of photoreceptor genes". J. Biol. Chem. 281 (2): 744–51. doi:10.1074/jbc.M509470200. PMID 16236706.
  • Faiyaz-Ul-Haque M, Zaidi SH, Al-Mureikhi MS, et al. (2007). "Mutations in the CHX10 gene in non-syndromic microphthalmia/anophthalmia patients from Qatar". Clin. Genet. 72 (2): 164–6. doi:10.1111/j.1399-0004.2007.00846.x. PMID 17661825.


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