Ultimopharyngeal body
| Ultimopharyngeal body | |
|---|---|
| Details | |
| Precursor | fourth pharyngeal pouch |
| Gives rise to | parafollicular cells |
| Identifiers | |
| Latin | corpus ultimopharyngeum |
| MeSH | D014460 |
| TE | E5.4.2.0.0.1.21 |
| Anatomical terminology | |
The ultimopharyngeal body or ultimobranchial body or ultimobranchial gland is a small organ found in the neck region of many animals.
In humans, the ultimobranchial body is an embryological structure that gives rise to the calcitonin-producing cells—also called parafollicular cells or C cells—of the thyroid gland. In humans, this body is a derivative of the ventral recess of the fourth pharyngeal pouch[1] (technically fifth, but that one is rudimentary and merges with the fourth). The cells that give rise to the parafollicular cells are actually derivatives of the endoderm[2]. These cells migrate and associate with the ultimopharyngeal body during development. Failure of development of ultimobranchial body is seen in DiGeorge syndrome.
References
- ↑ "ultimobranchial bodies" at Dorland's Medical Dictionary
- ↑ Johansson, E; Andersson, L; Örnros, J; Carlsson, T; Ingeson-Carlsson, C; Liang, S; Dahlberg, J; Jansson, S; Parrillo, L; Zoppoli, P; Barila, G. O; Altschuler, D. L; Padula, D; Lickert, H; Fagman, H; Nilsson, M (2015). "Revising the embryonic origin of thyroid C cells in mice and humans". Development. 142 (20): 3519–3528. doi:10.1242/dev.126581. PMC 4631767. PMID 26395490.
External links
- ent/534 at eMedicine
- hednk-022—Embryo Images at University of North Carolina
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