UTP20

UTP20
Identifiers
AliasesUTP20, DRIM, 1A6/DRIM, small subunit processome component
External IDsMGI: 1917933 HomoloGene: 38373 GeneCards: UTP20
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q23.2Start101,280,109 bp[1]
End101,386,616 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

27340

70683

Ensembl

ENSG00000120800

ENSMUSG00000004356

UniProt

O75691

Q5XG71

RefSeq (mRNA)

NM_014503

NM_175158

RefSeq (protein)

NP_055318

NP_780367

Location (UCSC)Chr 12: 101.28 – 101.39 MbChr 10: 88.75 – 88.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Small subunit processome component 20 homolog is a protein that in humans is encoded by the UTP20 gene.[5][6][7][8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000120800 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004356 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Schwirzke M, Gnirke A, Bork P, Tarin D, Weidle UH (Aug 1998). "Differential gene expression in mammary carcinoma cell lines: identification of DRIM, a new gene down-regulated in metastasis". Anticancer Res. 18 (3A): 1409–21. PMID 9673349.
  6. ↑ Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ (Dec 2004). "The small-subunit processome is a ribosome assembly intermediate". Eukaryot Cell. 3 (6): 1619–26. doi:10.1128/EC.3.6.1619-1626.2004. PMC 539036. PMID 15590835.
  7. ↑ Peng WT, Robinson MD, Mnaimneh S, Krogan NJ, Cagney G, Morris Q, Davierwala AP, Grigull J, Yang X, Zhang W, Mitsakakis N, Ryan OW, Datta N, Jojic V, Pal C, Canadien V, Richards D, Beattie B, Wu LF, Altschuler SJ, Roweis S, Frey BJ, Emili A, Greenblatt JF, Hughes TR (Jul 2003). "A panoramic view of yeast noncoding RNA processing". Cell. 113 (7): 919–33. doi:10.1016/S0092-8674(03)00466-5. PMID 12837249.
  8. ↑ "Entrez Gene: UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)".

Further reading

  • Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
  • Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
  • Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Goodison S, Viars C, Grazzini M, Urquidi V (2004). "The interrelationship between DRIM gene expression and cytogenetic and phenotypic characteristics in human breast tumor cell lines". BMC Genomics. 4: 39. doi:10.1186/1471-2164-4-39. PMC 222913. PMID 14503924.
  • Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
  • Xing X, Du X, Lu Z, Ning T, Su X, Ke Y (2005). "Characterization of the promoter of 1A6/DRIM, a novel cancer-related gene and identification of its transcriptional activator". Gene. 344: 161–9. doi:10.1016/j.gene.2004.09.036. PMID 15656982.
  • Yang L, Zhao J, Lü W, Li Y, Du X, Ning T, Lu G, Ke Y (2006). "KIAA0649, a 1A6/DRIM-interacting protein with the oncogenic potential". Biochem. Biophys. Res. Commun. 334 (3): 884–90. doi:10.1016/j.bbrc.2005.06.179. PMID 16053918.
  • Liu J, Du X, Ke Y (2006). "Mapping nucleolar localization sequences of 1A6/DRIM". FEBS Lett. 580 (5): 1405–10. doi:10.1016/j.febslet.2006.01.064. PMID 16458307.
  • Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
  • Wang Y, Liu J, Zhao H, Lü W, Zhao J, Yang L, Li N, Du X, Ke Y (2007). "Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing". Biochim. Biophys. Acta. 1773 (6): 863–8. doi:10.1016/j.bbamcr.2007.04.002. PMID 17498821.


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