UNQ1887

SPPL3
Identifiers
AliasesSPPL3, IMP2, MDHV1887, PRO4332, PSH1, PSL4, UNQ1887, signal peptide peptidase like 3
External IDsMGI: 1891433 HomoloGene: 15563 GeneCards: SPPL3
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q24.31Start120,762,510 bp[1]
End120,904,371 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

121665

74585

Ensembl

ENSG00000157837

ENSMUSG00000029550

UniProt

Q8TCT6

Q9CUS9

RefSeq (mRNA)

NM_139015

NM_029012

RefSeq (protein)

NP_620584

NP_083288

Location (UCSC)Chr 12: 120.76 – 120.9 MbChr 5: 115.01 – 115.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Signal peptide peptidase 3, also known as UNQ1887, is a human gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000157837 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029550 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: UNQ1887 signal peptide peptidase 3".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Weihofen A, Binns K, Lemberg MK, et al. (2002). "Identification of signal peptide peptidase, a presenilin-type aspartic protease". Science. 296 (5576): 2215–8. doi:10.1126/science.1070925. PMID 12077416.
  • Grigorenko AP, Moliaka YK, Korovaitseva GI, Rogaev EI (2003). "Novel class of polytopic proteins with domains associated with putative protease activity". Biochemistry Mosc. 67 (7): 826–35. doi:10.1023/A:1016365227942. PMID 12139484.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Friedmann E, Lemberg MK, Weihofen A, et al. (2005). "Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins". J. Biol. Chem. 279 (49): 50790–8. doi:10.1074/jbc.M407898200. PMID 15385547.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Krawitz P, Haffner C, Fluhrer R, et al. (2006). "Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3". J. Biol. Chem. 280 (47): 39515–23. doi:10.1074/jbc.M501645200. PMID 15998642.
  • Nyborg AC, Ladd TB, Jansen K, et al. (2006). "Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase". FASEB J. 20 (10): 1671–9. doi:10.1096/fj.06-5762com. PMID 16873890.


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