UBE3C

UBE3C
Identifiers
Aliases	UBE3C, HECTH2, ubiquitin protein ligase E3C
External IDs	MGI: 2140998 HomoloGene: 8783 GeneCards: UBE3C
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	157,269,372 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	29,676,092 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• protein binding; • ubiquitin-protein transferase activity; • transferase activity; • ubiquitin protein ligase activity; • ubiquitin conjugating enzyme activity;
Cellular component	• proteasome complex; • intracellular; • cell nucleus; • cytoplasm;
Biological process	• protein polyubiquitination; • protein ubiquitination; • ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	9690
	100763
	ENSG00000009335
	ENSMUSG00000039000
	Q15386
	Q80U95
	NM_014671
	NM_133907
	NP_055486
	NP_598668
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-protein ligase E3C is an enzyme that in humans is encoded by the UBE3C gene.^[5]^[6]^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000009335 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039000 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Nomura N, Miyajima N, Sazuka T, Tanaka A, Kawarabayasi Y, Sato S, Nagase T, Seki N, Ishikawa K, Tabata S (Dec 1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1". DNA Res. 1 (1): 27–35. doi:10.1093/dnares/1.1.27. PMID 7584026.
↑ You J, Pickart CM (Jun 2001). "A HECT domain E3 enzyme assembles novel polyubiquitin chains". J Biol Chem. 276 (23): 19871–8. doi:10.1074/jbc.M100034200. PMID 11278995.
↑ "Entrez Gene: UBE3C ubiquitin protein ligase E3C".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
You J, Wang M, Aoki T, et al. (2003). "Proteolytic targeting of transcriptional regulator TIP120B by a HECT domain E3 ligase". J. Biol. Chem. 278 (26): 23369–75. doi:10.1074/jbc.M212887200. PMID 12692129.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nomura N, Miyajima N, Sazuka T, et al. (1995). "Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement)". DNA Res. 1 (1): 47–56. doi:10.1093/dnares/1.1.47. PMID 7584028.

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