Terpinen-4-ol

Terpinen-4-ol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.008.396
MeSH terpinenol-4
UNII
Properties
C10H18O
Molar mass 154.25 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Terpinen-4-ol is an isomer of terpineol with a molecular weight of 154.249. It has an antibacterial and antifungal effect.

It is considered the primary active ingredient of tea tree oil.[1] It is also the compound of highest concentration in the essential oil of nutmeg.

Terpinen-4-ol occurs in Juniperus communis and is thought to be the reason this wood is highly resistant to rot. Norwegian farmers used to exploit this by making fence poles out of juniper. The concentration is higher in the alpine subspecies of juniper, but occurs in both subspecies.

Additional images

Synthesis

References

  1. Hammer, K. A.; Carson, C. F.; Riley, T. V. (2012). "Effects of Melaleuca alternifolia (Tea Tree) Essential Oil and the Major Monoterpene Component Terpinen-4-ol on the Development of Single- and Multistep Antibiotic Resistance and Antimicrobial Susceptibility". Antimicrobial Agents and Chemotherapy. 56 (2): 909–915. doi:10.1128/AAC.05741-11. PMC 3264233. PMID 22083482.
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