TXNDC2

TXNDC2
Identifiers
AliasesTXNDC2, SPTRX, SPTRX1, thioredoxin domain containing 2
External IDsMGI: 2389312 HomoloGene: 41856 GeneCards: TXNDC2
Gene location (Human)
Chr.Chromosome 18 (human)[1]
Band18p11.22Start9,885,726 bp[1]
End9,889,275 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

84203

213272

Ensembl

ENSG00000168454

ENSMUSG00000050612

UniProt

Q86VQ3

Q6P902

RefSeq (mRNA)

NM_032243
NM_001098529

NM_001146002
NM_153519

RefSeq (protein)

NP_001091999
NP_115619

NP_001139474
NP_705739

Location (UCSC)Chr 18: 9.89 – 9.89 MbChr 17: 65.64 – 65.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Thioredoxin domain-containing protein 2 is a protein that in humans is encoded by the TXNDC2 gene.[5][6][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000168454 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050612 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  6. ↑ Miranda-Vizuete A, Ljung J, Damdimopoulos AE, Gustafsson JA, Oko R, Pelto-Huikko M, Spyrou G (Aug 2001). "Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa" (PDF). J Biol Chem. 276 (34): 31567–74. doi:10.1074/jbc.M101760200. PMID 11399755.
  7. ↑ "Entrez Gene: TXNDC2 thioredoxin domain containing 2 (spermatozoa)".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Jiménez A, Johansson C, Ljung J, et al. (2002). "Human spermatid-specific thioredoxin-1 (Sptrx-1) is a two-domain protein with oxidizing activity". FEBS Lett. 530 (1–3): 79–84. doi:10.1016/S0014-5793(02)03417-8. PMID 12387870.
  • Sadek CM, Damdimopoulos AE, Pelto-Huikko M, et al. (2002). "Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells". Genes Cells. 6 (12): 1077–90. doi:10.1046/j.1365-2443.2001.00484.x. PMID 11737268.


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