TUBE1

TUBE1
Identifiers
AliasesTUBE1, TUBE, dJ142L7.2, tubulin epsilon 1
External IDsMGI: 1919174 HomoloGene: 17762 GeneCards: TUBE1
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6q21Start112,070,777 bp[1]
End112,087,529 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51175

71924

Ensembl

ENSG00000074935

ENSMUSG00000019845

UniProt

Q9UJT0

Q9D6T1

RefSeq (mRNA)

NM_016262

NM_028006

RefSeq (protein)

NP_057346

NP_082282

Location (UCSC)Chr 6: 112.07 – 112.09 MbChr 10: 39.13 – 39.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tubulin, epsilon 1 is a protein in humans that is encoded by the TUBE1 gene.[5] This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000074935 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019845 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Tubulin, epsilon 1".

Further reading

  • Chang P, Giddings TH, Winey M, Stearns T (January 2003). "Epsilon-tubulin is required for centriole duplication and microtubule organization". Nature Cell Biology. 5 (1): 71–6. doi:10.1038/ncb900. PMID 12510196.
  • Zanic M, Stear JH, Hyman AA, Howard J (October 2009). May RC, ed. "EB1 recognizes the nucleotide state of tubulin in the microtubule lattice". PLoS One. 4 (10): e7585. doi:10.1371/journal.pone.0007585. PMC 2761489. PMID 19851462.
  • Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. doi:10.1038/71350. PMID 10620804.


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