TTC4

TTC4
Identifiers
AliasesTTC4, tetratricopeptide repeat domain 4, CNS1
External IDsMGI: 1919604 HomoloGene: 31249 GeneCards: TTC4
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p32.3Start54,715,822 bp[1]
End54,742,657 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

7268

72354

Ensembl

ENSG00000243725

ENSMUSG00000025413

UniProt

O95801

Q8R3H9

RefSeq (mRNA)

NM_004623
NM_001291333

NM_001172073
NM_028209

RefSeq (protein)

NP_001278262
NP_004614

NP_001165544
NP_082485

Location (UCSC)Chr 1: 54.72 – 54.74 MbChr 4: 106.66 – 106.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tetratricopeptide repeat protein 4 is a protein that in humans is encoded by the TTC4 gene.[5][6]

The 34-amino acid tetratricopeptide repeat (TPR) motif is found in a variety of proteins and may mediate protein-protein or protein-membrane interactions.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000243725 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025413 - Ensembl, May 2017
  3. "Human PubMed Reference:".
  4. "Mouse PubMed Reference:".
  5. Su G, Roberts T, Cowell JK (Sep 1999). "TTC4, a novel human gene containing the tetratricopeptide repeat and mapping to the region of chromosome 1p31 that is frequently deleted in sporadic breast cancer". Genomics. 55 (2): 157–63. doi:10.1006/geno.1998.5633. PMID 9933562.
  6. 1 2 "Entrez Gene: TTC4 tetratricopeptide repeat domain 4".

Further reading

  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Lan S, Wang H, Jiang H, et al. (2003). "Direct interaction between alpha-actinin and hepatitis C virus NS5B". FEBS Lett. 554 (3): 289–94. doi:10.1016/S0014-5793(03)01163-3. PMID 14623081.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hey Y, Brintnell B, James LA, Varley JM (2000). "Assignment of TTC4 to human chromosome band 1p31.3 and a pseudogene TTC4P to 7p14→p13 by in situ hybridization". Cytogenet. Cell Genet. 88 (3–4): 272–4. doi:10.1159/000015536. PMID 10828607.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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