TTC3

TTC3
Identifiers
AliasesTTC3, DCRR1, RNF105, TPRDIII, tetratricopeptide repeat domain 3
External IDsMGI: 1276539 HomoloGene: 2487 GeneCards: TTC3
Gene location (Human)
Chr.Chromosome 21 (human)[1]
Band21q22.13Start37,073,226 bp[1]
End37,203,112 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

7267

22129

Ensembl

ENSG00000182670

ENSMUSG00000040785

UniProt

P53804

O88196

RefSeq (mRNA)

NM_009441

RefSeq (protein)
Location (UCSC)Chr 21: 37.07 – 37.2 MbChr 16: 94.37 – 94.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tetratricopeptide repeat protein 3 is a protein that in humans is encoded by the TTC3 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000182670 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000040785 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Tsukahara F, Hattori M, Muraki T, Sakaki Y (Mar 1997). "Identification and cloning of a novel cDNA belonging to tetratricopeptide repeat gene family from Down syndrome-critical region 21q22.2". J Biochem. 120 (4): 820–7. doi:10.1093/oxfordjournals.jbchem.a021485. PMID 8947847.
  6. ↑ "Entrez Gene: TTC3 tetratricopeptide repeat domain 3".

Further reading

  • Ohira M, Ootsuyama A, Suzuki E, et al. (1996). "Identification of a novel human gene containing the tetratricopeptide repeat domain from the Down syndrome region of chromosome 21". DNA Res. 3 (1): 9–16. doi:10.1093/dnares/3.1.9. PMID 8724848.
  • Eki T, Abe M, Naitou M, et al. (1997). "Cloning and characterization of novel gene, DCRR1, expressed from Down's syndrome critical region of human chromosome 21q22.2". DNA Seq. 7 (3–4): 153–64. doi:10.3109/10425179709034031. PMID 9254009.
  • Dahmane N, Ghezala GA, Gosset P, et al. (1998). "Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome". Genomics. 48 (1): 12–23. doi:10.1006/geno.1997.5146. PMID 9503011.
  • Rachidi M, Lopes C, Gassanova S, et al. (2000). "Regional and cellular specificity of the expression of TPRD, the tetratricopeptide Down syndrome gene, during human embryonic development". Mech. Dev. 93 (1–2): 189–93. doi:10.1016/S0925-4773(00)00259-8. PMID 10781955.
  • Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Berto G, Camera P, Fusco C, et al. (2007). "The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase". J. Cell Sci. 120 (Pt 11): 1859–67. doi:10.1242/jcs.000703. PMID 17488780.


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