TMED1

TMED1
Identifiers
AliasesTMED1, IL1RL1LG, Il1rl1l, Tp24, p24g1, transmembrane p24 trafficking protein 1
External IDsMGI: 106201 HomoloGene: 21360 GeneCards: TMED1
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19p13.2Start10,832,438 bp[1]
End10,836,318 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

11018

17083

Ensembl

ENSG00000099203

ENSMUSG00000032180

UniProt

Q13445

Q3V009

RefSeq (mRNA)

NM_006858

NM_010744
NM_001324510

RefSeq (protein)

NP_006849

NP_001311439
NP_034874

Location (UCSC)Chr 19: 10.83 – 10.84 MbChr 9: 21.51 – 21.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane emp24 domain-containing protein 1 is a protein that in humans is encoded by the TMED1 gene.[5][6][7]

The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1). This protein lacks any similarity to other interleukin 1 ligands. The functional significance of its interaction with IL1RL1 is not known.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000099203 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032180 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Chan WL, Pejnovic N, Lee CA, Al-Ali NA (Jul 2001). "Human IL-18 receptor and ST2L are stable and selective markers for the respective type 1 and type 2 circulating lymphocytes". J Immunol. 167 (3): 1238–44. doi:10.4049/jimmunol.167.3.1238. PMID 11466339.
  6. ↑ Gayle MA, Slack JL, Bonnert TP, Renshaw BR, Sonoda G, Taguchi T, Testa JR, Dower SK, Sims JE (Jun 1996). "Cloning of a putative ligand for the T1/ST2 receptor". J Biol Chem. 271 (10): 5784–9. doi:10.1074/jbc.271.10.5784. PMID 8621446.
  7. 1 2 "Entrez Gene: TMED1 transmembrane emp24 protein transport domain containing 1".

Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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