Solute carrier family 10 member 4
SLC10A4 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | SLC10A4, P4, solute carrier family 10 member 4 | ||||||||||||||||||||||||
External IDs | MGI: 3606480 HomoloGene: 15495 GeneCards: SLC10A4 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 4: 48.48 – 48.49 Mb | Chr 5: 73.01 – 73.01 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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Solute carrier family 10 member 4 is a protein that in humans is encoded by the SLC10A4 gene.[5] In mice, it appears to promote acidification of synaptic vesicles containing monoamines, enhancing their uptake, and is co-expressed with VMAT2 and VAChT.[6]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000145248 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029219 - Ensembl, May 2017
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: Solute carrier family 10 member 4". Retrieved 2016-04-17.
- ↑ Larhammar M, Patra K, Blunder M, Emilsson L, Peuckert C, Arvidsson E, Rönnlund D, Preobraschenski J, Birgner C, Limbach C, Widengren J, Blom H, Jahn R, Wallén-Mackenzie Å, Kullander K (March 2015). "SLC10A4 is a vesicular amine-associated transporter modulating dopamine homeostasis". Biological Psychiatry. 77 (6): 526–36. doi:10.1016/j.biopsych.2014.07.017. PMID 25176177.
Further reading
- Splinter PL, Lazaridis KN, Dawson PA, LaRusso NF (November 2006). "Cloning and expression of SLC10A4, a putative organic anion transport protein". World Journal of Gastroenterology. 12 (42): 6797–805. doi:10.3748/wjg.v12.i42.6797. PMC 4087434. PMID 17106928.
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