Scott W. Lowe

Scott W. Lowe
Born 1963
Racine, Wisconsin
Nationality American
Citizenship American
Alma mater
Known for p53
Scientific career
Fields Cancer Genetics
Institutions

Scott William Lowe (born October 4, 1963) is the Chair of the Cancer Biology and Genetics Program at Memorial Sloan Kettering Cancer Center. He is recognized for his research on the tumor suppressor gene, p53, which is mutated in nearly half of cancers.

Early life and education

Lowe was born in 1963 in Racine, Wisconsin. He enrolled at University of Wisconsin-Madison in chemical engineering in 1982 before changing his major to biology. He worked for two years after graduation as a lab technician working in a hypercholesterolemia lab.[1] He did his PhD at Massachusetts Institute of Technology on the role of p53 in cancer development.[2] He stayed at MIT to do a postdoc with David Housman and Tyler Jacks.[3]

Career

He moved from MIT to Cold Spring Harbor Laboratory continuing his work on p53. He started as an assistant professor in 1995, and eventually became Deputy Director of the Cancer Center. Much of his work has focused on tumor suppressor genes, and their relation to drug resistance after chemotherapy treatment.[4] In collaboration with Gregory Hannon and Stephen Elledge, he has made extensive use of RNA interference to study the roles of tumor suppressor genes. He moved to Sloan Kettering in 2011 to lead the department of Cancer Biology and Genetics. He has been an HHMI Investigator since 2005.[5]

Awards

References

  1. ↑ "Biography 38: Scott William Lowe (1963 - ) :: DNA Learning Center". Dnalc.org. Retrieved 2017-03-10.
  2. ↑ "Dr Scott W Lowe". Atthelimits.org. Retrieved 2017-03-10.
  3. ↑ "Oncology at the Limits 2015 : Speaker biographies". The Lancet. Retrieved 2017-03-10.
  4. ↑ "Biologist Scott Lowe Joins Memorial Sloan Kettering | Memorial Sloan Kettering Cancer Center". Mskcc.org. Retrieved 2017-03-10.
  5. ↑ "Scott W. Lowe, PhD". HHMI.org. Retrieved 2017-03-10.
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