SRGAP1

SRGAP1
Identifiers
AliasesSRGAP1, ARHGAP13, NMTC2, SLIT-ROBO Rho GTPase activating protein 1
External IDsMGI: 2152936 HomoloGene: 56898 GeneCards: SRGAP1
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q14.2Start63,844,293 bp[1]
End64,162,221 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

57522

117600

Ensembl

ENSG00000196935

ENSMUSG00000020121

UniProt

Q7Z6B7

Q91Z69

RefSeq (mRNA)

NM_020762
NM_001346201

NM_001081037
NM_001242411

RefSeq (protein)

NP_001333130
NP_065813

NP_001074506
NP_001229340

Location (UCSC)Chr 12: 63.84 – 64.16 MbChr 10: 121.78 – 122.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SLIT-ROBO Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the SRGAP1 gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000196935 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020121 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Wong K, Ren XR, Huang YZ, Xie Y, Liu G, Saito H, Tang H, Wen L, Brady-Kalnay SM, Mei L, Wu JY, Xiong WC, Rao Y (Oct 2001). "Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway". Cell. 107 (2): 209–21. doi:10.1016/S0092-8674(01)00530-X. PMID 11672528.
  6. ↑ "Entrez Gene: SRGAP1 SLIT-ROBO Rho GTPase activating protein 1".

Further reading

  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Katoh M, Katoh M (2004). "FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains". Int. J. Mol. Med. 11 (6): 791–7. doi:10.3892/ijmm.11.6.791. PMID 12736724.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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