SNPedia

SNPedia
Content
Description a wiki of human single-nucleotide polymorphisms and genotypes
Data types
captured		 single-nucleotide polymorphisms, genotypes, genes, variation
Organisms Homo sapiens
Contact
Primary citation PMID 22140107
Access
Website www.snpedia.com
Download URL www.snpedia.com/index.php/Bulk
Web service URL bots.snpedia.com/api.php
Miscellaneous
License Creative Commons Attribution-Noncommercial-Share Alike 3.0 United States License
Curation policy wiki

SNPedia (pronounced "snipedia") is a wiki-based bioinformatics web site that serves as a database of single nucleotide polymorphisms (SNPs). Each article on a SNP provides a short description, links to scientific articles and personal genomics web sites, as well as microarray information about that SNP. Thus SNPedia may support the interpretation of results of personal genotyping from, e.g., 23andMe and similar companies.[1]

SNPedia is a semantic wiki, powered by MediaWiki and the Semantic MediaWiki extension.

SNPedia was created, and is run by, geneticist Greg Lennon[2] and programmer Mike Cariaso,[3] who at the time of the site's founding were both located in Bethesda, Maryland.[4]

As of 4 September 2017, the website has 107,123 SNPs in its database.[5] The number of SNPs in SNPedia has doubled roughly once every 14 months since August 2007.[6]

Promethease

An associated computer program called Promethease, also developed by the SNPedia team, allows users to compare personal genetics results against the SNPedia database, generating a report with information about a person's attributes, such as propensity to diseases, based on the presence of specific SNPs within their genome.[3]

In May 2008 Cariaso, using Promethease, won an online contest sponsored by 23andMe to determine as much information as possible about an anonymous woman based only on her genome. Cariaso won in all three categories of "accuracy, creativity and cleverness".[7] In 2009, the anonymous woman ("Lilly Mendel") was revealed to be 23andMe co-founder Linda Avey, allowing a direct comparison between her actual traits and those predicted by Promethease a year earlier.[8]

Reception

In a June 2008 article on personal genomics, a doctor from the Southern Illinois University School of Medicine said:

In January 2011, technology journalist Ronald Bailey posted the full result of his Promethease report online. Writing about his decision in Reason magazine, he stated:

See also

References

  1. ↑ Michael Cariaso (2007-12-17). "SNPedia: A Wiki for Personal Genomics". Bio-IT World.
  2. ↑ John Carey (2008-10-23). "Is Genetic Testing Really Good for Your Health?". LEX18.
  3. 1 2 Daniel MacArthur (2008-11-05). "Nature special issue on personal genomics". scienceblogs.com. Archived from the original on 2008-11-09. Retrieved 2008-11-06.
  4. ↑ "Genes R Us" (PDF). Science. 319 (5860): 139. 11 January 2008. doi:10.1126/science.319.5860.139b.
  5. ↑ "SNPedia:FAQ".
  6. ↑ SNPedia: a wiki supporting personal genome annotation, interpretation and analysis, Michael Cariaso and Greg Lennon, Nucleic Acids Research, 2011, 1–5
  7. ↑ And the Winner Is..., Matthew Crenson, The Spittoon, May 14, 2008
  8. ↑ "SNPedia:User:Lilly Mendel".
  9. ↑ Lisa Nainggolan (2008-06-23). "Letting the genome out of the bottle: Unraveling the genetics of heart disease". theheart.org by WebMD.
  10. ↑ Ronald Bailey (January 2011). "I'll Show You My Genome. Will You Show Me Yours?". Reason.
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