SADS coronavirus

SADS-CoV is a corona virus related to Rhinolophus Bat coronavirus HKU2. It is transmitted through the feces of horseshoe bats to pigs. Piglets less than 5 days old die with a probability of 90%. SADS-CoV was identified during the SARS outbreak caused by SARS-CoV in Guangdong 2013 onwards, where it caused the death of more than 24,000 piglets on 4 farms. Current research says that it cannot infect humans. The fear remains that such a virus can mutate and then become dangerous for humans. Researches as well made clear, while bats carry zoonotic viruses, they are very important for a well balanced ecosystem. Some for example eat mosquitos which carry dangerous viruses like malaria, yellow fever, chikungunya, zika and others. ^[1][2][3][4]

Detection

The SADS-CoV virus in the pigs was found to be 98.48% genetically identical to one collected in anal swabs of the Chinese rufous horseshoe bat (rhinolophus sinicus), Least horseshoe bat (rhinolopus pusillus), king horseshoe bat (rhinolopus rex), intermediate horseshoe bat (rhinolopus affinus). This is called metagenomics analysis. second-generation sequencing, also called NGS, was used. It was demonstrated that NGS, luciferase immunoprecipitation system serology and phyloge-netic analysis can be used even before the virus is isolated. ^[4]

References