Rich Carter

Rich G. Carter (born August 27, 1971, Dallas, TX) is Professor of Chemistry of the Department of Chemistry at Oregon State University. His research fields are synthetic organic chemistry in general and natural product synthesis. He is also the co-founder and CEO of a chemical manufacturing company Valliscor.[1]

Carter attended Gettysburg College for his undergraduate studies and the University of Texas at Austin for graduate school, earning his Ph.D. in 1997 under the tutelage of Professor Philip Magnus. He subsequently joined the laboratory of James D. White at OSU, as an NIH Postdoctoral Fellow. He was a faculty member at the University of Mississippi before relocating to Corvallis, Oregon in 2002.

His work includes investigations on selective catalysis, including the design, discovery, and study of systems that mediate fundamentally interesting and useful organic reactions. Main focuses of his laboratory are: Natural product synthesis, Diels-Alder approach to Biaryls, Hua Cat: a p-Dodecylphenylsulfonylamide-Based Proline Derivative for Practical Solutions to Organocatalysis, Asymmetric Selenide Oxidation / [2,3] Sigmatropic Rearrangement (ASOS Reaction). His research group has had a long-standing interest in the synthesis of complex, biological active natural products. Each target must possess a challenging structural motif(s) that is not well addressed by current synthetic strategy. Selected examples of broader importance include developing compounds with promising biological activity against clinically relevant pathogenic bacteria and for treatment of cancer. Current synthetic targets in Professor Carter's laboratory includes amphidinolides, azaspiracids, lycopodium alkaloids,[2] steroids etc.[3]

Notable contributions

Carter has developed proline based sulfonamide catalysts for many asymmetric transformations and a new method to generate biaryls using the Diels-Alder reaction.

Total syntheses accomplished

  • Siamenol (2007)
  • Amphidinolide B1 and Amphidinolide B2 (2008)
  • Lycopodine (2008)
  • Cermizine D (2012)
  • Amphidinolide F (2012)
  • 10-Hydroxy Lycopodium alkaloids (2013),[4][5]
  • Amphidinolide C (2013)
  • Mandelalide A (2016)
  • Halenaquinone (2018)

References

  1. ↑ Valliscor Website, Rich G. Carter, last accessed April 4, 2015 (website includes description of the company)
  2. ↑ Lycopodium Alkaloids: An Intramolecular Michael Reaction Approach
  3. ↑ Oregon State University Department of Chemistry Website, Rich G. Carter, last accessed April 4, 2015 (website includes photograph of Rich G. Carter)
  4. ↑ Toward a Unified Approach for the Lycopodines: Synthesis of 10-Hydroxylycopodine, Deacetylpaniculine, and Paniculine
  5. ↑ Unified Synthesis of 10-Oxygenated Lycopodium Alkaloids: Impact of C10-Stereochemistry on Reactivity
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