RcsR1 small RNA

RcsR1 sRNA
Predicted secondary structure and sequence conservation of RcsR1 small RNA
Identifiers
Rfam RF02552
Other data
Domain(s) Bacteria
GO 0040033,0032055
SO 0000370
PDB structures PDBe

RcsR1 (rhizobial cold and salinity stress riboregulator 1) trans-acting sRNA, formerly known as SmelC587, is a stress-related riboregulator, conserved in Sinorhizobium, Rhizobium and Agrobacterium. It contains highly conserved stem-loops involved in the interaction with several target mRNAs (PhoR, MotE, anti-σE1, GntR, FgA, TrpC). In Sinorhizobium meliloti RcsR1 less conserved central region is responsible for the species-specific interaction with the 5’UTR of autoinducer synthase encoding mRNA sinI. The interaction negatively influences sinI translation.[1]

See also


References

  1. Baumgardt, K; Šmídová, K; Rahn, H; Lochnit, G; Robledo, M; Evguenieva-Hackenberg, E (2015). "The stress-related, rhizobial small RNA RcsR1 destabilizes the autoinducer synthase encoding mRNA sinI in Sinorhizobium meliloti". RNA Biol. 13: 486–99. doi:10.1080/15476286.2015.1110673. PMC 4962803. PMID 26588798.
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