RAB5C

RAB5C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4KYI
Identifiers
Aliases	RAB5C, L1880, RAB5CL, RAB5L, RABL, member RAS oncogene family
External IDs	MGI: 105306 HomoloGene: 55533 GeneCards: RAB5C
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	42,155,044 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	100,738,215 bp[2]
RNA expression pattern
	; ;
	More reference expression data
Gene ontology
Molecular function	• nucleotide binding; • GTP binding; • protein binding; • GDP binding; • GTPase activity;
Cellular component	• melanosome; • lysosomal membrane; • endosome; • lipid droplet; • endocytic vesicle; • early endosome; • extracellular exosome; • membrane; • plasma membrane; • early endosome membrane; • azurophil granule membrane; • intracellular;
Biological process	• protein transport; • regulation of endocytosis; • plasma membrane to endosome transport; • neutrophil degranulation; • transport; • small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	5878
	19345
	ENSG00000108774
	ENSMUSG00000019173
	P51148
	P35278
	NM_001252039; NM_004583; NM_201434
	NM_024456; NM_001305003
	NP_001238968; NP_004574; NP_958842
	NP_001291932; NP_077776
	Wikidata
View/Edit Human	View/Edit Mouse

Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene.^[5]^[6] RAB5C belongs to the Ras-related protein family.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000108774 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019173 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Han HJ, Sudo K, Inazawa J, Nakamura Y (Jul 1996). "Isolation and mapping of a human gene (RABL) encoding a small GTP-binding protein homologous to the Ras-related RAB gene". Cytogenet Cell Genet. 73 (1–2): 137–9. doi:10.1159/000134325. PMID 8646882.
↑ "Entrez Gene: RAB5C RAB5C, member RAS oncogene family".

Albertsen HM, Smith SA, Mazoyer S, et al. (1994). "A physical map and candidate genes in the BRCA1 region on chromosome 17q12-21". Nat. Genet. 7 (4): 472–9. doi:10.1038/ng0894-472. PMID 7951316.
Alvarez-Dominguez C, Stahl PD (1999). "Interferon-gamma selectively induces Rab5a synthesis and processing in mononuclear cells". J. Biol. Chem. 273 (51): 33901–4. doi:10.1074/jbc.273.51.33901. PMID 9852039.
Bucci C, Chiariello M, Lattero D, et al. (1999). "Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1)". Biochem. Biophys. Res. Commun. 258 (3): 657–62. doi:10.1006/bbrc.1999.0651. PMID 10329441.
Clemens DL, Lee BY, Horwitz MA (2000). "Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate". Infect. Immun. 68 (5): 2671–84. doi:10.1128/IAI.68.5.2671-2684.2000. PMC 97474. PMID 10768959.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Merithew E, Stone C, Eathiraj S, Lambright DG (2003). "Determinants of Rab5 interaction with the N terminus of early endosome antigen 1". J. Biol. Chem. 278 (10): 8494–500. doi:10.1074/jbc.M211514200. PMID 12493736.
Kajiho H, Saito K, Tsujita K, et al. (2004). "RIN3: a novel Rab5 GEF interacting with amphiphysin II involved in the early endocytic pathway". J. Cell Sci. 116 (Pt 20): 4159–68. doi:10.1242/jcs.00718. PMID 12972505.
Chi A, Valencia JC, Hu ZZ, et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". J. Proteome Res. 5 (11): 3135–44. doi:10.1021/pr060363j. PMID 17081065.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000108774 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019173 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[pmid8646882-5] Han HJ, Sudo K, Inazawa J, Nakamura Y (Jul 1996). "Isolation and mapping of a human gene (RABL) encoding a small GTP-binding protein homologous to the Ras-related RAB gene". Cytogenet Cell Genet. 73 (1–2): 137–9. doi:10.1159/000134325. PMID 8646882.

[entrez-6] "Entrez Gene: RAB5C RAB5C, member RAS oncogene family".

RAB5C

References

Further reading