RAB3B

RAB3B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRAB3B, member RAS oncogene family
External IDsMGI: 1917158 HomoloGene: 2149 GeneCards: RAB3B
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p32.3Start51,907,956 bp[1]
End51,990,764 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

5865

69908

Ensembl

ENSG00000169213

ENSMUSG00000003411

UniProt

P20337

Q9CZT8

RefSeq (mRNA)

NM_002867

NM_023537

RefSeq (protein)

NP_002858

NP_076026

Location (UCSC)Chr 1: 51.91 – 51.99 MbChr 4: 108.88 – 108.94 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ras-related protein Rab-3B is a protein that in humans is encoded by the RAB3B gene.[5]

Interactions

RAB3B has been shown to interact with RPH3A.[6][7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000169213 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000003411 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: RAB3B RAB3B, member RAS oncogene family".
  6. ↑ Fukuda, Mitsunori (Apr 2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. United States. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. ISSN 0021-9258. PMID 12578829.
  7. ↑ Weber, E; Jilling T; Kirk K L (Mar 1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". J. Biol. Chem. UNITED STATES. 271 (12): 6963–71. doi:10.1074/jbc.271.12.6963. ISSN 0021-9258. PMID 8636125.

Further reading

  • Rousseau-Merck MF, Zahraoui A, Touchot N, et al. (1991). "Chromosome assignment of four RAS-related RAB genes". Hum. Genet. 86 (4): 350–4. doi:10.1007/BF00201831. PMID 1999336.
  • Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion". J. Biol. Chem. 264 (21): 12394–401. PMID 2501306.
  • Weber E, Berta G, Tousson A, et al. (1994). "Expression and polarized targeting of a rab3 isoform in epithelial cells". J. Cell Biol. 125 (3): 583–94. doi:10.1083/jcb.125.3.583. PMC 2119989. PMID 8175882.
  • Weber E, Jilling T, Kirk KL (1996). "Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells". J. Biol. Chem. 271 (12): 6963–71. doi:10.1074/jbc.271.12.6963. PMID 8636125.
  • Regazzi R, Ravazzola M, Iezzi M, et al. (1997). "Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells". J. Cell Sci. 109 (9): 2265–73. PMID 8886977.
  • Sidhu RS, Bhullar RP (2002). "Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin". Biochem. Biophys. Res. Commun. 289 (5): 1039–43. doi:10.1006/bbrc.2001.6113. PMID 11741295.
  • van IJzendoorn SC, Tuvim MJ, Weimbs T, et al. (2002). "Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells". Dev. Cell. 2 (2): 219–28. doi:10.1016/S1534-5807(02)00115-6. PMID 11832247.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
  • Yamamoto Y, Nishimura N, Morimoto S, et al. (2003). "Distinct roles of Rab3B and Rab13 in the polarized transport of apical, basolateral, and tight junctional membrane proteins to the plasma membrane". Biochem. Biophys. Res. Commun. 308 (2): 270–5. doi:10.1016/S0006-291X(03)01358-5. PMID 12901864.
  • Matsumoto M, Miki T, Shibasaki T, et al. (2004). "Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells". Proc. Natl. Acad. Sci. U.S.A. 101 (22): 8313–8. Bibcode:2004PNAS..101.8313M. doi:10.1073/pnas.0306709101. PMC 420391. PMID 15159548.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.


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