PyrR binding site
| PyrR binding site | |
|---|---|
 Predicted secondary structure and sequence conservation of PyrR | |
| Identifiers | |
| Symbol | PyrR |
| Rfam | RF00515 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Bacteria |
| SO | 0000233 |
| PDB structures | PDBe |
The PyrR binding site is an RNA element that is found upstream of a variety of genes involved in pyrimidine biosynthesis and transport.[1]
The RNA structure permits binding of PyrR protein which regulates pyrimidine biosynthesis in Bacillus subtilis. When the protein binds, a downstream terminator hairpin forms, repressing transcription of biosynthesis genes.[1]
References
- 1 2 Bonner, ER; D'Elia JN; Billips BK; Switzer RL (2001). "Molecular recognition of pyr mRNA by the Bacillus subtilis attenuation regulatory protein PyrR". Nucleic Acids Res. 29 (23): 4851&ndash, 4865. doi:10.1093/nar/29.23.4851. PMC 96680. PMID 11726695.
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