Psychosine

Psychosine
Names
	IUPAC name (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl β-D-galactopyranoside
Identifiers
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:16874;
ChemSpider	4444111;
KEGG	C01747;
PubChem CID	5280458;
	InChI InChI=1S/C24H47NO7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(27)18(25)17-31-24-23(30)22(29)21(28)20(16-26)32-24/h14-15,18-24,26-30H,2-13,16-17,25H2,1H3/b15-14+/t18-,19+,20+,21-,22-,23+,24+/m0/s1 Key: HHJTWTPUPVQKNA-PIIMIWFASA-N;
	SMILES CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O)N)O;
Properties
Chemical formula	C24H47NO7
Molar mass	461.64 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Psychosine is a highly cytotoxic lipid that accumulates in the nervous system in the absence of galactosylceramidase.^[1]

Chemically, it is a galactoside of sphingosine.

References

↑ Hawkins-Salsbury, J. A.; Parameswar, A. R.; Jiang, X; Schlesinger, P. H.; Bongarzone, E; Ory, D. S.; Demchenko, A. V.; Sands, M. S. (2013). "Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture". The Journal of Lipid Research. 54 (12): 3303–3311. doi:10.1194/jlr.M039610. PMC 3826678. PMID 24006512.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.