Proline rich 5 like

PRR5L
Identifiers
Aliases	PRR5L, PROTOR2, proline rich 5 like
External IDs	MGI: 1919696 HomoloGene: 11753 GeneCards: PRR5L
Gene location (Human)
Chr.	Chromosome 11 (human)[1]
End	36,465,204 bp[1]
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)[2]
End	101,883,027 bp[2]
Gene ontology
Molecular function	• ubiquitin protein ligase binding; • protein binding;
Cellular component	• TORC2 complex;
Biological process	• TORC2 signaling; • negative regulation of protein phosphorylation; • positive regulation of phosphatidylinositol 3-kinase signaling; • negative regulation of signal transduction; • positive regulation of protein phosphorylation; • regulation of fibroblast migration; • cellular response to oxidative stress; • positive regulation of mRNA catabolic process; • positive regulation of intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
	79899
	72446
	ENSG00000135362
	ENSMUSG00000032841
	Q6MZQ0
	A2AVJ5
	NM_024841; NM_001160167; NM_001160168; NM_001160169
	NM_001083810; NM_001110849; NM_175181; NM_001355625
	NP_001153639; NP_001153640; NP_001153641; NP_079117
	NP_001077279; NP_001104319; NP_780390; NP_001342554
	Wikidata
View/Edit Human	View/Edit Mouse

Proline rich 5 like is a protein that in humans is encoded by the PRR5L gene. ^[5]

References

Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR (2007). "Identification of Protor as a novel Rictor-binding component of mTOR complex-2". Biochem. J. 405 (3): 513–22. doi:10.1042/BJ20070540. PMC 2267312. PMID 17461779.
Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLoS ONE. 5 (9): e12862. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.