Pregnancy zone protein

PZP
Identifiers
AliasesPZP, CPAMD6, alpha-2-macroglobulin like
External IDsHomoloGene: 74452 GeneCards: PZP
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12p13.31Start9,148,840 bp[1]
End9,208,370 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

5858

n/a

Ensembl

ENSG00000126838

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

NM_002864

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 12: 9.15 – 9.21 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Pregnancy zone protein is a protein that in humans is encoded by the PZP gene.[3]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000126838 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Entrez Gene: PZP pregnancy-zone protein".

Further reading

  • Marynen P, Devriendt K, Van den Berghe H, Cassiman JJ (1990). "A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin". FEBS Lett. 262 (2): 349–52. doi:10.1016/0014-5793(90)80226-9. PMID 1692292.
  • Christensson A, Laurell CB, Lilja H (1991). "Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors". Eur. J. Biochem. 194 (3): 755–63. doi:10.1111/j.1432-1033.1990.tb19466.x. PMID 1702714.
  • Devriendt K, Van den Berghe H, Cassiman JJ, Marynen P (1991). "Primary structure of pregnancy zone protein. Molecular cloning of a full-length PZP cDNA clone by the polymerase chain reaction". Biochim. Biophys. Acta. 1088 (1): 95–103. doi:10.1016/0167-4781(91)90157-H. PMID 1989698.
  • Sand O, Folkersen J, Westergaard JG, Sottrup-Jensen L (1986). "Characterization of human pregnancy zone protein. Comparison with human alpha 2-macroglobulin". J. Biol. Chem. 260 (29): 15723–35. PMID 2415522.
  • Sottrup-Jensen L, Birkedal-Hansen H (1989). "Human fibroblast collagenase-alpha-macroglobulin interactions. Localization of cleavage sites in the bait regions of five mammalian alpha-macroglobulins". J. Biol. Chem. 264 (1): 393–401. PMID 2462561.
  • Sottrup-Jensen L, Sand O, Kristensen L, Fey GH (1989). "The alpha-macroglobulin bait region. Sequence diversity and localization of cleavage sites for proteinases in five mammalian alpha-macroglobulins". J. Biol. Chem. 264 (27): 15781–9. PMID 2476433.
  • Devriendt K, Zhang J, van Leuven F, et al. (1989). "A cluster of alpha 2-macroglobulin-related genes (alpha 2 M) on human chromosome 12p: cloning of the pregnancy-zone protein gene and an alpha 2M pseudogene". Gene. 81 (2): 325–34. doi:10.1016/0378-1119(89)90193-5. PMID 2478422.
  • Christensen U, Simonsen M, Harrit N, Sottrup-Jensen L (1990). "Pregnancy zone protein, a proteinase-binding macroglobulin. Interactions with proteinases and methylamine". Biochemistry. 28 (24): 9324–31. doi:10.1021/bi00450a012. PMID 2692707.
  • Sottrup-Jensen L, Folkersen J, Kristensen T, Tack BF (1985). "Partial primary structure of human pregnancy zone protein: extensive sequence homology with human alpha 2-macroglobulin". Proc. Natl. Acad. Sci. U.S.A. 81 (23): 7353–7. doi:10.1073/pnas.81.23.7353. PMC 392144. PMID 6209714.
  • Philip A, Bostedt L, Stigbrand T, O'Connor-McCourt MD (1994). "Binding of transforming growth factor-beta (TGF-beta) to pregnancy zone protein (PZP). Comparison to the TGF-beta-alpha 2-macroglobulin interaction". Eur. J. Biochem. 221 (2): 687–93. doi:10.1111/j.1432-1033.1994.tb18781.x. PMID 7513640.
  • Jensen PE, Arbelaez LF, Shanbhag VP, Stigbrand T (1996). "Preparation and characterization of a C-terminal fragment of pregnancy zone protein corresponding to the receptor-binding peptide from human alpha 2-macroglobulin". Biochim. Biophys. Acta. 1293 (2): 254–8. doi:10.1016/0167-4838(95)00257-x. PMID 8620037.
  • Valnickova Z, Thogersen IB, Christensen S, et al. (1996). "Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein". J. Biol. Chem. 271 (22): 12937–43. doi:10.1074/jbc.271.22.12937. PMID 8662763.
  • Arbeláez LF, Bergmann U, Tuuttila A, et al. (1997). "Interaction of matrix metalloproteinases-2 and -9 with pregnancy zone protein and alpha2-macroglobulin". Arch. Biochem. Biophys. 347 (1): 62–8. doi:10.1006/abbi.1997.0309. PMID 9344465.
  • Chiabrando GA, Vides MA, Sánchez MC (2002). "Differential binding properties of human pregnancy zone protein- and alpha2-macroglobulin-proteinase complexes to low-density lipoprotein receptor-related protein". Arch. Biochem. Biophys. 398 (1): 73–8. doi:10.1006/abbi.2001.2659. PMID 11811950.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell. Proteomics. 3 (4): 311–26. doi:10.1074/mcp.M300127-MCP200. PMID 14718574.
  • Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMC 1850943. PMID 16335952.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Barrera DI, Matheus LM, Stigbrand T, Arbeláez LF (2007). "Proteolytic hydrolysis and purification of the LRP/alfa-2-macroglobulin receptor domain from alpha-macroglobulins". Protein Expr. Purif. 53 (1): 112–8. doi:10.1016/j.pep.2006.12.008. PMID 17257854.


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