Pospiviroid RY motif stem loop

Pospiviroid RY motif stem loop
Predicted secondary structure and sequence conservation of Pospi_RY
Identifiers
Symbol Pospi_RY
Rfam RF00362
Other data
RNA type Cis-reg
Domain(s) Viroids
SO 0000233
PDB structures PDBe

The Pospiviroid RY motif stem loop is an RNA element found in Pospiviroids such as potato spindle tuber viroid (PSTVd). The RY nucleotide sequence motif (5'-ACAGG and CUCUUCC-5') in PSTVd, is thought to bind with the tomato protein Virp1. The exact function of this motif and the significance of Virp1 binding is unknown. It is however thought that RY motifs are essential for establishing a viroid infection.[1]

References

  1. Gozmanova, M; Denti MA; Minkov IN; Tsagris M; Tabler M (2003). "Characterization of the RNA motif responsible for the specific interaction of potato spindle tuber viroid RNA (PSTVd) and the tomato protein Virp1". Nucleic Acids Res. 31 (19): 5534–5543. doi:10.1093/nar/gkg777. PMC 206474. PMID 14500815.
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