Plasmodium reichenowi
Plasmodium reichenowi is a malaria parasite that infects chimpanzees.[1]
Plasmodium reichenowi | |
---|---|
Scientific classification | |
Kingdom: | Protista |
Phylum: | Apicomplexa |
Class: | Aconoidasida |
Order: | Haemosporida |
Family: | Plasmodiidae |
Genus: | Plasmodium |
Species: | P. reichenowi |
Binomial name | |
Plasmodium reichenowi | |
Description
Plasmodium reichenowi is classified into the subgenus Laverania.[2] It is a chimpanzee malaria parasite that is evolutionarily related to the human malaria parasite P. falciparum.[3] P. reichenowi and P. falciparum are phylogenetically close to each other.[1] A high-quality reference genome for P. reichenowi was produced from Illumina reads using de novo assembly and post hoc improvement. Excluding the subtelomeres, the genome is almost completely co-linear with P. falciparum and share almost identical gene content emphasizing their recent shared ancestry. The vast majority of these approximately 5,000 ‘core’ genes are common to both parasites, with only three genes present in P. reichenowi that are missing in P. falciparum and only one in P. falciparum that is absent from P. reichenowi.[4]
Host pathology
Plasmodium reichenowi normally only infects chimpanzees.[5] A young chimpanzee, followed before and after release to a sanctuary, in a semi-free ranging enclosure located in an equatorial forest, showed fever and strong anaemia associated with a high P. reichenowi infection, shortly after release. The animal recovered from anaemia after several months despite recurrent infection with other Plasmodium species.[2]
Geographical occurrence
Chimpanzees live mainly in central and western Africa, so this would determine the host range for P. reichenowi.[5]
See also
References
- 1 2 "Plasmodium reichenowi". sanger.ac.uk. Retrieved 21 February 2018.
- 1 2 Herbert, Anaïs; Boundenga, Larson; Meyer, Anne; Diamella, Nancy Moukodoum; Okouga, Alain Prince; Arnathau, Céline; Durand, Patrick; Magnus, Julie; Ngoubangoye, Barthélémy; Willaume, Eric; Ba, Cheikh Tidiane; Rougeron, Virginie; Renaud, François; Ollomo, Benjamin; Prugnolle, Franck. "Malaria-like symptoms associated with a natural Plasmodium reichenowi infection in a chimpanzee". doi:10.1186/s12936-015-0743-y. PMC 4502519.
- ↑ Altaf, Lal A.; Goldman, LalIra F.; Campbell, Gary H. "Primary structure of the 25-kilodalton ookinete antigen from Plasmodium reichenowi". doi:10.1016/0166-6851(90)90139-D.
- ↑ Otto, Thomas D.; Rayner, Julian C.; Böhme, Ulrike; Pain, Arnab; Spottiswoode, Natasha; Sanders, Mandy; Quail, Michael; Ollomo, Benjamin; Renaud, François; Thomas, Alan W.; Prugnolle, Franck; Conway, David J.; Newbold, Chris; Berriman, Matthew. "Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts". doi:10.1038/ncomms5754. Retrieved 21 February 2018.
- 1 2 "Malaria Host Range". malaria.com. Retrieved 21 February 2018.