Phenomics

Phenomics is an area of biology concerned with the measurement of phenomes (a phenome is the set of physical and biochemical traits belonging to a given organism) as they change in response to genetic mutation and environmental influences.[1] It is used in functional genomics, pharmaceutical research, metabolic engineering and increasingly in phylogenetics.[2]

An important field of research today is trying to improve, both qualitatively and quantitatively, the capacity to measure phenomes. This includes developing high-throughput measurement systems.

For example, the Australian Plant Phenomics Facility, an initiative of the Australian government, has developed a number of new instruments for comprehensive and fast measurements of phenotypes in both the lab and the field.

See also

References

  1. ↑ Houle, David; Govindaraju, Diddahally R.; Omholt, Stig (2010). "Phenomics: the next challenge". Nature Reviews Genetics. 11 (12): 855–866. doi:10.1038/nrg2897. PMID 21085204.
  2. ↑ O'Leary, M. A.; Bloch, J. I.; Flynn, J. J.; Gaudin, T. J.; Giallombardo, A.; Giannini, N. P.; Goldberg, S. L.; Kraatz, B. P.; Luo, Z.-X.; Meng, J.; Ni, X.; Novacek, M. J.; Perini, F. A.; Randall, Z.; Rougier, G. W.; Sargis, E. J.; Silcox, M. T.; Simmons, N. B.; Spaulding, M.; Velazco, P. M.; Weksler, M.; Wible, J. R.; Cirranello, A. L. (2013). "The placental mammal ancestor and the post-K-Pg radiation of placentals". Science. 332: 662–667.

Further reading

  • Schilling, C.H.; Edwards, J.S.; Palsson, B.O. (1999). "Toward metabolic phenomics: analysis of genomic data using flux balances". Biotechnology Progress. 15 (3): 288–295. doi:10.1021/bp9900357. PMID 10356245.
  • Gerlai, R. (2002). "Phenomics: fiction or the future?". Trends in Neurosciences. 25 (10): 506–509. doi:10.1016/S0166-2236(02)02250-6. PMID 12220878.
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