Para tertiary butylphenol formaldehyde resin

Illustration of allergic contact dermatitis

Para tertiary butylphenol formaldehyde resin also known as p-tert-butylphenol-formaldehyde resin (PTBP-FR) or 4-(1,1-dimethylethyl) phenol (PTBP Formaldehyde) is a phenol-formaldehyde resin found in commercial adhesives, and in particular in adhesives used to bond leather and rubber. It has broad usage in a large variety of industries and can be found in many household items and textile products, and in particular it is used in the manufacture of shoes.[1][2]

Contact Dermatitis

It is noteworthy because this resin can cause severe allergic contact dermatitis in a significant percentage of individuals who come into contact with the resin. Most cases of dermatitis result from contact with shoes, watchbands, belts, fabric glues, wet suits, handbags, purses, wallets, hats, fabric glues, furniture and upholstery glues, wood glues, waterproof glues, rubber handled tools, dental bonding resins, box adhesives, disposable diapers, lip liner, and rubber athletic insoles. Use of PTBP-FR in manufacturing is ubiquitous across numerous industries and commercial products, but most commonly its usage in the manufacture of shoes is implicated in the majority of cases involving contact dermatitis.[3][4][5]

References

  1. ↑ Herro, Elise; Jacob, Sharon E. (1 March 2012). "p-tert-Butylphenol formaldehyde resin and its impact on children". Dermatitis: Contact, Atopic, Occupational, Drug. 23 (2): 86–88. doi:10.1097/DER.0b013e31824a64ff. PMID 22653125.
  2. ↑ Allergens: p-TERT-BUTYLPHENOL FORMALDEHYDE RESIN
  3. ↑ Shono, Mamiko; Ezoe, Kazuhiko; Kaniwa, Masa-Aki; Ikarashi, Yokhiaki; Kojima, Shigeo; Nakamura, Akitada (1 April 1991). "Allergic contact dermatitis from para-tertiary-butylphenol-formaldehyde resin (PTBP-FR) in athletic tape and leather adhesive". Contact Dermatitis. 24 (4): 281–288. doi:10.1111/j.1600-0536.1991.tb01723.x – via Wiley Online Library.
  4. ↑ Foussereau, J.; Cavelier, C.; Selig, D. (1 October 1976). "Occupational eczema from para-tertiary-butylphenol formaldehyde resins: A review of the sensitizing resins". Contact Dermatitis. 2 (5): 254–258. doi:10.1111/j.1600-0536.1976.tb03043.x – via Wiley Online Library.
  5. ↑ Handley, J.; Todd, D.; Bingham, A.; Corbett, R.; Burrows, D. (1 September 1993). "Allergic contact dermatitis from para-tertiary-butylphenol-formaldehyde resin (PTBP-F-R) in Northern Ireland". Contact Dermatitis. 29 (3): 144–146. doi:10.1111/j.1600-0536.1993.tb03512.x – via Wiley Online Library.
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