PURG

PURG
Identifiers
AliasesPURG, PURG-A, PURG-B, purine-rich element binding protein G, purine rich element binding protein G, PURGA, PURGB
External IDsMGI: 1922279 HomoloGene: 22747 GeneCards: PURG
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8p12Start30,995,802 bp[1]
End31,033,715 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

29942

75029

Ensembl

ENSG00000172733

ENSMUSG00000049184

UniProt

Q9UJV8

Q8R4E6

RefSeq (mRNA)

NM_001015508
NM_013357
NM_001323311
NM_001323312

NM_001098233
NM_152821

RefSeq (protein)

NP_001015508
NP_001310240
NP_001310241
NP_037489

NP_001091703
NP_690034

Location (UCSC)Chr 8: 31 – 31.03 MbChr 8: 33.39 – 33.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Purine-rich element binding protein G is a protein that in humans is encoded by the PURG gene.[5]

Function

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A (PURA). The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. Two transcript variants encoding different isoforms have been found for this gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000172733 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049184 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 "Entrez Gene: Purine-rich element binding protein G". Retrieved 2015-12-27.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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