PPP3R2

PPP3R2
Identifiers
AliasesPPP3R2, PPP3RL, protein phosphatase 3 regulatory subunit B, beta
External IDsMGI: 107171 HomoloGene: 133815 GeneCards: PPP3R2
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q31.1Start101,591,615 bp[1]
End101,595,021 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

5535

19059

Ensembl

ENSG00000188386

ENSMUSG00000028310

UniProt

Q96LZ3

Q63811

RefSeq (mRNA)

NM_147180

NM_001004025

RefSeq (protein)

NP_671709

NP_001004025

Location (UCSC)Chr 9: 101.59 – 101.6 MbChr 4: 49.68 – 49.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.[5][6] Among its related pathways are MAPK signaling pathway[7] and GPCR pathway.[8] GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CHP1.[9]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000188386 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028310 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Liu L, Zhang J, Yuan J, Dang Y, Yang C, Chen X, Xu J, Yu L (May 2005). "Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis". Mol Biol Rep. 32 (1): 41–5. doi:10.1007/s11033-004-4250-4. PMID 15865209.
  6. ↑ "Entrez Gene: PPP3R2 protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform".
  7. ↑ "PathCards :: MAPK signaling pathway Pathway and related pathways". pathcards.genecards.org. Retrieved 2015-09-08.
  8. ↑ "PathCards :: GPCR Pathway Pathway and related pathways". pathcards.genecards.org. Retrieved 2015-09-08.
  9. ↑ Database, GeneCards Human Gene. "PPP3R2 Gene - GeneCards | CANB2 Protein | CANB2 Antibody". www.genecards.org. Retrieved 2015-09-08.

Further reading

  • Mukai H, Chang CD, Tanaka H, et al. (1991). "cDNA cloning of a novel testis-specific calcineurin B-like protein". Biochem. Biophys. Res. Commun. 179 (3): 1325–30. doi:10.1016/0006-291X(91)91718-R. PMID 1718268.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology. 303 (1): 174–80. doi:10.1006/viro.2002.1676. PMID 12482669.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Koefoed-Nielsen PB, Karamperis N, Højskov C, et al. (2007). "The calcineurin activity profiles of cyclosporin and tacrolimus are different in stable renal transplant patients". Transpl. Int. 19 (10): 821–7. doi:10.1111/j.1432-2277.2006.00359.x. PMID 16961774.
  • Saeki M, Irie Y, Ni L, et al. (2007). "Calcineurin potentiates the activation of procaspase-3 by accelerating its proteolytic maturation". J. Biol. Chem. 282 (16): 11786–94. doi:10.1074/jbc.M609347200. PMID 17324936.
  • Jang H, Cho EJ, Youn HD (2007). "A new calcineurin inhibition domain in Cabin1". Biochem. Biophys. Res. Commun. 359 (1): 129–35. doi:10.1016/j.bbrc.2007.05.066. PMID 17531200.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.