PIGW

PIGW
Identifiers
AliasesPIGW, Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
External IDsMGI: 1917575 HomoloGene: 6243 GeneCards: PIGW
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q12Start36,535,020 bp[1]
End36,539,310 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

284098

70325

Ensembl

ENSG00000275600
ENSG00000277161

ENSMUSG00000045140

UniProt

Q7Z7B1

Q8C398

RefSeq (mRNA)

NM_178517
NM_001346754
NM_001346755

NM_001077636
NM_027388
NM_001363112

RefSeq (protein)

NP_001333683
NP_001333684
NP_848612

NP_001071104
NP_081664
NP_001350041

Location (UCSC)Chr 17: 36.54 – 36.54 MbChr 11: 84.88 – 84.88 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene. [5]

Function

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).

References

  1. 1 2 3 ENSG00000277161 GRCh38: Ensembl release 89: ENSG00000275600, ENSG00000277161 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045140 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Phosphatidylinositol glycan anchor biosynthesis class W". Retrieved 2016-10-29.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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