PI4K2B

PI4K2B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPI4K2B, PI4KIIB, PIK42B, phosphatidylinositol 4-kinase type 2 beta
External IDsMGI: 1914323 HomoloGene: 32405 GeneCards: PI4K2B
Orthologs
SpeciesHumanMouse
Entrez

55300

67073

Ensembl

n/a

ENSMUSG00000029186

UniProt

Q8TCG2

Q8CBQ5

RefSeq (mRNA)

NM_018323

NM_025951
NM_028744

RefSeq (protein)

NP_060793

NP_080227
NP_083020

Location (UCSC)n/aChr 5: 52.74 – 52.77 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphatidylinositol 4-kinase type 2-beta is an enzyme that in humans is encoded by the PI4K2B gene.[4][5]

References

  1. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029186 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:".
  3. ↑ "Mouse PubMed Reference:".
  4. ↑ Balla A, Tuymetova G, Barshishat M, Geiszt M, Balla T (May 2002). "Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments". J Biol Chem. 277 (22): 20041–50. doi:10.1074/jbc.M111807200. PMID 11923287.
  5. ↑ "Entrez Gene: PI4K2B phosphatidylinositol 4-kinase type 2 beta".

Further reading

  • Griffioen M, van der Meijden ED, Slager EH, et al. (2008). "Identification of phosphatidylinositol 4-kinase type II beta as HLA class II-restricted target in graft versus leukemia reactivity". Proc. Natl. Acad. Sci. U.S.A. 105 (10): 3837–42. doi:10.1073/pnas.0712250105. PMC 2268788. PMID 18316730.
  • Jones DR, Bultsma Y, Keune WJ, et al. (2006). "Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta". Mol. Cell. 23 (5): 685–95. doi:10.1016/j.molcel.2006.07.014. PMID 16949365.
  • Srivastava R, Sinha RK, Subrahmanyam G (2006). "Type II phosphatidylinositol 4-kinase beta associates with TCR-CD3 zeta chain in Jurkat cells". Mol. Immunol. 43 (5): 454–63. doi:10.1016/j.molimm.2005.03.009. PMID 16337488.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Wei YJ, Sun HQ, Yamamoto M, et al. (2003). "Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP". J. Biol. Chem. 277 (48): 46586–93. doi:10.1074/jbc.M206860200. PMID 12324459.
  • Mora S, Durham PL, Smith JR, et al. (2002). "NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway". J. Biol. Chem. 277 (30): 27494–500. doi:10.1074/jbc.M203669200. PMID 12011096.
  • Huang C, Handlogten ME, Miller RT (2002). "Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor". J. Biol. Chem. 277 (23): 20293–300. doi:10.1074/jbc.M200831200. PMID 11907035.


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