PHLDB1

PHLDB1
Identifiers
AliasesPHLDB1, LL5A, pleckstrin homology like domain family B member 1
External IDsMGI: 2143230 HomoloGene: 15903 GeneCards: PHLDB1
Gene location (Human)
Chr.Chromosome 11 (human)[1]
Band11q23.3Start118,606,440 bp[1]
End118,658,038 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23187

102693

Ensembl

ENSG00000019144

ENSMUSG00000048537

UniProt

Q86UU1

Q6PDH0

RefSeq (mRNA)

NM_001144758
NM_001144759
NM_015157

NM_153537

RefSeq (protein)

NP_001138230
NP_001138231
NP_055972
NP_001138231.1

NP_705765

Location (UCSC)Chr 11: 118.61 – 118.66 MbChr 9: 44.69 – 44.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pleckstrin homology-like domain family B member 1 is a protein that in humans is encoded by the PHLDB1 gene.[5][6]

The first PHLDB1 cDNA was cloned from a rat pituitary cDNA library and named as LL5 after the clone number.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000019144 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000048537 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Katoh M, Katoh M (Oct 2003). "Identification and characterization of human LL5A gene and mouse Ll5a gene in silico". Int J Oncol. 23 (5): 1477–83. doi:10.3892/ijo.23.5.1477. PMID 14532993.
  6. ↑ "Entrez Gene: PHLDB1 pleckstrin homology-like domain, family B, member 1".
  7. ↑ Levi L, Hanukoglu I, Raikhinstein M, Kohen F, Koch Y (16 November 1993). "Cloning of LL5, a novel protein encoding cDNA from a rat pituitary library". Biochimica et Biophysica Acta. 1216 (2): 342–4. doi:10.1016/0167-4781(93)90171-9. PMID 8241284.

Further reading

  • Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
  • Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  • Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR (October 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem. J. 351 (Pt 1): 19–31. doi:10.1042/0264-6021:3510019. PMC 1221362. PMID 11001876.
  • Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y (May 2010). "Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta". J. Cell Biol. 189 (5): 901–17. doi:10.1083/jcb.200910095. PMC 2878951. PMID 20513769.
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