PHAX

PHAX
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPHAX, RNUXA, phosphorylated adaptor for RNA export
External IDsMGI: 1891839 HomoloGene: 10558 GeneCards: PHAX
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5q23.2Start126,600,268 bp[1]
End126,627,252 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51808

56698

Ensembl

ENSG00000164902

ENSMUSG00000008301

UniProt

Q9H814

Q9JJT9

RefSeq (mRNA)

NM_032177

NM_001162989
NM_019996

RefSeq (protein)

NP_115553

NP_001156461
NP_064380

Location (UCSC)Chr 5: 126.6 – 126.63 MbChr 18: 56.56 – 56.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphorylated adapter RNA export protein is a protein that in humans is encoded by the PHAX gene.[5][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164902 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000008301 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Ohno M, Segref A, Bachi A, Wilm M, Mattaj IW (May 2000). "PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation". Cell. 101 (2): 187–98. doi:10.1016/S0092-8674(00)80829-6. PMID 10786834.
  6. ↑ "Entrez Gene: RNUXA RNA U, small nuclear RNA export adaptor (phosphorylation regulated)".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Segref A, Mattaj IW, Ohno M (2001). "The evolutionarily conserved region of the U snRNA export mediator PHAX is a novel RNA-binding domain that is essential for U snRNA export". RNA. 7 (3): 351–60. doi:10.1017/S1355838201002278. PMC 1370092. PMID 11333016.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Boulon S, Verheggen C, Jady BE, et al. (2005). "PHAX and CRM1 are required sequentially to transport U3 snoRNA to nucleoli". Mol. Cell. 16 (5): 777–87. doi:10.1016/j.molcel.2004.11.013. PMID 15574332.
  • Watkins NJ, Lemm I, Ingelfinger D, et al. (2005). "Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex". Mol. Cell. 16 (5): 789–98. doi:10.1016/j.molcel.2004.11.012. PMID 15574333.


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