PGK1

PGK1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPGK1, HEL-S-68p, MIG10, PGKA, phosphoglycerate kinase 1
External IDsMGI: 97555 HomoloGene: 21542 GeneCards: PGK1
Gene location (Human)
Chr.X chromosome (human)[1]
BandXq21.1Start77,910,739 bp[1]
End78,129,296 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

5230

18655

Ensembl

ENSG00000102144

ENSMUSG00000062070

UniProt

P00558

P09411

RefSeq (mRNA)

NM_000291

NM_008828

RefSeq (protein)

NP_000282

NP_032854

Location (UCSC)Chr X: 77.91 – 78.13 MbChr X: 106.19 – 106.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Phosphoglycerate kinase 1 is an enzyme that in humans is encoded by the PGK1 gene.[5][6][7]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

[[File:
GlycolysisGluconeogenesis_WP534go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to WikiPathwaysgo to articlego to Entrezgo to article
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GlycolysisGluconeogenesis_WP534go to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to articlego to WikiPathwaysgo to articlego to Entrezgo to article
|{{{bSize}}}px|alt=Glycolysis and Gluconeogenesis edit]]
Glycolysis and Gluconeogenesis edit
  1. ↑ The interactive pathway map can be edited at WikiPathways: "GlycolysisGluconeogenesis_WP534".

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000102144 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062070 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ Michelson AM, Markham AF, Orkin SH (May 1983). "Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase". Proc Natl Acad Sci U S A. 80 (2): 472–6. doi:10.1073/pnas.80.2.472. PMC 393400. PMID 6188151.
  6. ↑ Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD (May 1985). "Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase]". Gene. 32 (3): 409–17. doi:10.1016/0378-1119(84)90016-7. PMID 6099325.
  7. ↑ "Entrez Gene: PGK1 phosphoglycerate kinase 1".

Further reading

  • Vishwanatha JK, Jindal HK, Davis RG (1992). "The role of primer recognition proteins in DNA replication: association with nuclear matrix in HeLa cells". J. Cell Sci. 101. ( Pt 1): 25–34. PMID 1533225.
  • Fujii H, Kanno H, Hirono A, et al. (1992). "A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria". Blood. 79 (6): 1582–5. PMID 1547346.
  • Maeda M, Bawle EV, Kulkarni R, et al. (1992). "Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation". Blood. 79 (10): 2759–62. PMID 1586722.
  • Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID 1602151.
  • Kumble KD, Vishwanatha JK (1992). "Immunoelectron microscopic analysis of the intracellular distribution of primer recognition proteins, annexin 2 and phosphoglycerate kinase, in normal and transformed cells". J. Cell Sci. 99. ( Pt 4): 751–8. PMID 1837552.
  • Maeda M, Yoshida A (1991). "Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3". Blood. 77 (6): 1348–52. PMID 2001457.
  • Jindal HK, Vishwanatha JK (1990). "Functional identity of a primer recognition protein as phosphoglycerate kinase". J. Biol. Chem. 265 (12): 6540–3. PMID 2324090.
  • Johnson P, Friedmann T (1990). "Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK". Gene. 88 (2): 207–13. doi:10.1016/0378-1119(90)90033-N. PMID 2347494.
  • Pfeifer GP, Steigerwald SD, Mueller PR, et al. (1989). "Genomic sequencing and methylation analysis by ligation mediated PCR". Science. 246 (4931): 810–3. doi:10.1126/science.2814502. PMID 2814502.
  • Michelson AM, Blake CC, Evans ST, Orkin SH (1985). "Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain". Proc. Natl. Acad. Sci. U.S.A. 82 (20): 6965–9. doi:10.1073/pnas.82.20.6965. PMC 391290. PMID 2995995.
  • McCarrey JR, Thomas K (1987). "Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene". Nature. 326 (6112): 501–5. doi:10.1038/326501a0. PMID 3453121.
  • Fujii H, Yoshida A (1981). "Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia". Proc. Natl. Acad. Sci. U.S.A. 77 (9): 5461–5. doi:10.1073/pnas.77.9.5461. PMC 350080. PMID 6933565.
  • Fujii H, Chen SH, Akatsuka J, et al. (1981). "Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia". Proc. Natl. Acad. Sci. U.S.A. 78 (4): 2587–90. doi:10.1073/pnas.78.4.2587. PMC 319394. PMID 6941312.
  • Huang IY, Welch CD, Yoshida A (1980). "Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence". J. Biol. Chem. 255 (13): 6412–20. PMID 7391027.
  • Fujii H, Krietsch WK, Yoshida A (1980). "A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency". J. Biol. Chem. 255 (13): 6421–3. PMID 7391028.
  • Huang IY, Fujii H, Yoshida A (1981). "Structure and function of normal and variant human phosphoglycerate kinase". Hemoglobin. 4 (5–6): 601–9. doi:10.3109/03630268008997730. PMID 7440217.
  • Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank". Gene. 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
  • Hershkovitz M, Riggs AD (1995). "Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes". Proc. Natl. Acad. Sci. U.S.A. 92 (6): 2379–83. doi:10.1073/pnas.92.6.2379. PMC 42487. PMID 7892275.


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