PGAM5

PGAM family member 5, mitochondrial serine/threonine protein phosphatase
Identifiers
Symbol	PGAM5
Entrez	192111
PDB	5MUF
UniProt	Q96HS1
Other data
Locus	Chr. 12 q

PGAM5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MXO, 3O0T
Identifiers
Aliases	PGAM5, BXLBV68, PGAM family member 5, mitochondrial serine/threonine protein phosphatase
External IDs	MGI: 1919792 HomoloGene: 14597 GeneCards: PGAM5
Gene location (Human)
Chr.	Chromosome 12 (human)[1]
End	132,722,734 bp[1]
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)[2]
End	110,269,913 bp[2]
Gene ontology
Molecular function	• phosphatase activity; • phosphoprotein phosphatase activity; • hydrolase activity; • GTPase activator activity; • protein binding; • macromolecular complex binding; • protein serine/threonine phosphatase activity;
Cellular component	• integral component of membrane; • membrane; • mitochondrion; • mitochondrial outer membrane;
Biological process	• protein dephosphorylation; • necroptotic process; • programmed cell death; • dephosphorylation; • positive regulation of GTPase activity; • macroautophagy;
	Sources:Amigo / QuickGO
Orthologs
	192111
	72542
	ENSG00000247077
	ENSMUSG00000029500
	Q96HS1
	Q8BX10
	NM_138575; NM_001170543; NM_001170544
	NM_001163538; NM_028273
	NP_001164014; NP_001164015; NP_612642
	NP_001157010; NP_082549
	Wikidata
View/Edit Human	View/Edit Mouse

PGAM family member 5 (PGAM5), also known as mitochondrial Serine/threonine-protein phosphatase PGAM5 is related to phosphoglycerate mutase family. It, in humans, is encoded by the PGAM5 gene on chromosome 12.^[5]^[6]

1 2 3 GRCh38: Ensembl release 89: ENSG00000247077 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029500 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: PGAM5, PGAM family member 5".
↑ "UniProtKB: Q96HS1".

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000247077 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029500 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[entrez-5] "Entrez Gene: PGAM5, PGAM family member 5".

[uniprot-6] "UniProtKB: Q96HS1".