PELO

PELO
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X52
Identifiers
Aliases	PELO, PRO1770, CGI-17, pelota homolog (Drosophila), pelota mRNA surveillance and ribosome rescue factor
External IDs	MGI: 2145154 HomoloGene: 6835 GeneCards: PELO
Gene location (Human)
Chr.	Chromosome 5 (human)[1]
End	52,804,046 bp[1]
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)[2]
End	115,090,186 bp[2]
Gene ontology
Molecular function	• endonuclease activity; • nuclease activity; • hydrolase activity; • metal ion binding; • protein binding; • ribosome binding;
Cellular component	• cell nucleus; • cytoplasm;
Biological process	• cell cycle; • RNA surveillance; • cell proliferation; • nuclear-transcribed mRNA catabolic process, non-stop decay; • chromosome organization; • nucleic acid phosphodiester bond hydrolysis; • cell division; • translation; • endoderm development; • stem cell population maintenance; • positive regulation of BMP signaling pathway; • ribosome disassembly; • mesenchymal to epithelial transition; • nonfunctional rRNA decay; • nuclear-transcribed mRNA catabolic process, no-go decay;
	Sources:Amigo / QuickGO
Orthologs
	53918
	105083
	ENSG00000152684
	ENSMUSG00000042275
	Q9BRX2
	Q80X73
	NM_015946
	NM_134058
	NP_057030
	NP_598819
	Wikidata
View/Edit Human	View/Edit Mouse

Protein pelota homolog is a protein that in humans is encoded by the PELO gene.^[5]^[6]

This gene encodes a protein which contains a conserved nuclear localization signal. The encoded protein may have a role in spermatogenesis, cell cycle control, and in meiotic cell division.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000152684 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042275 - Ensembl, May 2017
↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Shamsadin R, Adham IM, von Beust G, Engel W (Nov 2000). "Molecular cloning, expression and chromosome location of the human pelota gene PELO". Cytogenet Cell Genet. 90 (1–2): 75–8. doi:10.1159/000015667. PMID 11060452.
1 2 "Entrez Gene: PELO pelota homolog (Drosophila)".

Cheli Y, Kanaji S, Jacquelin B, et al. (2007). "Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2". Biochim. Biophys. Acta. 1769 (9–10): 546–58. doi:10.1016/j.bbaexp.2007.06.004. PMC 2682338. PMID 17669516.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000152684 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042275 - Ensembl, May 2017

[3] "Human PubMed Reference:".

[4] "Mouse PubMed Reference:".

[pmid11060452-5] Shamsadin R, Adham IM, von Beust G, Engel W (Nov 2000). "Molecular cloning, expression and chromosome location of the human pelota gene PELO". Cytogenet Cell Genet. 90 (1–2): 75–8. doi:10.1159/000015667. PMID 11060452.

[entrez-6] 1 2 "Entrez Gene: PELO pelota homolog (Drosophila)".

PELO

References

Further reading