PDE6C

PDE6C
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesPDE6C, ACHM5, COD4, PDEA2, phosphodiesterase 6C
External IDsMGI: 105956 HomoloGene: 4521 GeneCards: PDE6C
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10q23.33Start93,612,588 bp[1]
End93,666,010 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

5146

110855

Ensembl

ENSG00000095464

ENSMUSG00000024992

UniProt

P51160

Q91ZQ1

RefSeq (mRNA)

NM_006204

NM_001170959
NM_033614

RefSeq (protein)

NP_006195

NP_001164430
NP_291092

Location (UCSC)Chr 10: 93.61 – 93.67 MbChr 19: 38.13 – 38.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000095464 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024992 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime".

Further reading

  • Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Bertazolli-Filho R, Ghosh S, Huang W, et al. (2001). "Molecular evidence that human ocular ciliary epithelium expresses components involved in phototransduction". Biochem. Biophys. Res. Commun. 284 (2): 317–25. doi:10.1006/bbrc.2001.4970. PMID 11394879.
  • Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Gao YQ, Danciger M, Longmuir R, et al. (1999). "Screening of the gene encoding the alpha'-subunit of cone cGMP-PDE in patients with retinal degenerations". Invest. Ophthalmol. Vis. Sci. 40 (8): 1818–22. PMID 10393054.
  • Feshchenko EA, Andreeva SG, Suslova VA, et al. (1996). "Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement". FEBS Lett. 381 (1–2): 149–52. doi:10.1016/0014-5793(96)00104-4. PMID 8641425.
  • Viczian AS, Piriev NI, Farber DB (1996). "Isolation and characterization of a cDNA encoding the alpha' subunit of human cone cGMP-phosphodiesterase". Gene. 166 (2): 205–11. doi:10.1016/0378-1119(95)00585-4. PMID 8543163.
  • Piriev NI, Viczian AS, Ye J, et al. (1996). "Gene structure and amino acid sequence of the human cone photoreceptor cGMP-phosphodiesterase alpha' subunit (PDEA2) and its chromosomal localization to 10q24". Genomics. 28 (3): 429–35. doi:10.1006/geno.1995.1171. PMID 7490077.
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