Ormdl sphingolipid biosynthesis regulator 3

ORMDL3
Identifiers
AliasesORMDL3, ORMDL sphingolipid biosynthesis regulator 3
External IDsMGI: 1913862 HomoloGene: 57032 GeneCards: ORMDL3
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q21.1Start39,921,041 bp[1]
End39,927,601 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

94103

66612

Ensembl

ENSG00000172057

ENSMUSG00000038150

UniProt

Q8N138

Q9CPZ6

RefSeq (mRNA)

NM_139280
NM_001320801
NM_001320802
NM_001320803
NM_016471

NM_025661

RefSeq (protein)

NP_001307730
NP_001307731
NP_001307732
NP_644809

NP_079937

Location (UCSC)Chr 17: 39.92 – 39.93 MbChr 11: 98.58 – 98.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

ORMDL sphingolipid biosynthesis regulator 3 is a protein that in humans is encoded by the ORMDL3 gene. [5]


References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000172057 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038150 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: ORMDL sphingolipid biosynthesis regulator 3". Retrieved 2017-03-08.

Further reading

  • Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO (2007). "Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma". Nature. 448 (7152): 470–3. doi:10.1038/nature06014. PMID 17611496.
  • Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO (2007). "Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma". Nature. 448 (7152): 470–3. doi:10.1038/nature06014. PMID 17611496.
  • Hirota T, Harada M, Sakashita M, Doi S, Miyatake A, Fujita K, Enomoto T, Ebisawa M, Yoshihara S, Noguchi E, Saito H, Nakamura Y, Tamari M (2008). "Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population". J. Allergy Clin. Immunol. 121 (3): 769–70. doi:10.1016/j.jaci.2007.09.038. PMID 18155279.
  • Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG (2008). "ORMDL3 gene is associated with asthma in three ethnically diverse populations". Am. J. Respir. Crit. Care Med. 177 (11): 1194–200. doi:10.1164/rccm.200711-1644OC. PMC 2408437. PMID 18310477.
  • Galanter J, Choudhry S, Eng C, Nazario S, Rodríguez-Santana JR, Casal J, Torres-Palacios A, Salas J, Chapela R, Watson HG, Meade K, LeNoir M, Rodríguez-Cintrón W, Avila PC, Burchard EG (2008). "ORMDL3 gene is associated with asthma in three ethnically diverse populations". Am. J. Respir. Crit. Care Med. 177 (11): 1194–200. doi:10.1164/rccm.200711-1644OC. PMC 2408437. PMID 18310477.
  • Tavendale R, Macgregor DF, Mukhopadhyay S, Palmer CN (2008). "A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications". J. Allergy Clin. Immunol. 121 (4): 860–3. doi:10.1016/j.jaci.2008.01.015. PMID 18395550.
  • Tavendale R, Macgregor DF, Mukhopadhyay S, Palmer CN (2008). "A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications". J. Allergy Clin. Immunol. 121 (4): 860–3. doi:10.1016/j.jaci.2008.01.015. PMID 18395550.
  • Sleiman PM, Annaiah K, Imielinski M, Bradfield JP, Kim CE, Frackelton EC, Glessner JT, Eckert AW, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson W, Garris M, Gunnlaugsson S, Chiavacci RM, Allen J, Spergel J, Grundmeier R, Grunstein MM, Magnusson M, Bisgaard H, Grant SF, Hakonarson H (2008). "ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry". J. Allergy Clin. Immunol. 122 (6): 1225–7. doi:10.1016/j.jaci.2008.06.041. PMID 18760456.
  • Sleiman PM, Annaiah K, Imielinski M, Bradfield JP, Kim CE, Frackelton EC, Glessner JT, Eckert AW, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson W, Garris M, Gunnlaugsson S, Chiavacci RM, Allen J, Spergel J, Grundmeier R, Grunstein MM, Magnusson M, Bisgaard H, Grant SF, Hakonarson H (2008). "ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry". J. Allergy Clin. Immunol. 122 (6): 1225–7. doi:10.1016/j.jaci.2008.06.041. PMID 18760456.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.