OSR2 (gene)

OSR2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesOSR2, odd-skipped related transciption factor 2
External IDsMGI: 1930813 HomoloGene: 14200 GeneCards: OSR2
Gene location (Human)
Chr.Chromosome 8 (human)[1]
Band8q22.2Start98,944,403 bp[1]
End98,952,104 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

116039

107587

Ensembl

ENSG00000164920

ENSMUSG00000022330

UniProt

Q8N2R0

Q91ZD1

RefSeq (mRNA)

NM_001142462
NM_001286841
NM_053001

NM_054049

RefSeq (protein)

NP_001135934
NP_001273770
NP_443727

NP_473390

Location (UCSC)Chr 8: 98.94 – 98.95 MbChr 15: 35.3 – 35.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein odd-skipped-related 2 is a protein that in humans is encoded by the OSR2 gene.[5] In mice, it is involved in the development of the palate and in suppressing the formation of teeth after the eruption of adult teeth.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164920 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022330 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: OSR2 odd-skipped related 2 (Drosophila)".

Further reading

  • Kawai S, Kato T, Inaba H, et al. (2005). "Odd-skipped related 2 splicing variants show opposite transcriptional activity". Biochem. Biophys. Res. Commun. 328 (1): 306–11. doi:10.1016/j.bbrc.2004.12.173. PMID 15670784.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Lan Y, Ovitt CE, Cho ES, et al. (2004). "Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis". Development. 131 (13): 3207–16. doi:10.1242/dev.01175. PMID 15175245.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Katoh M (2003). "Molecular cloning and characterization of OSR1 on human chromosome 2p24". Int. J. Mol. Med. 10 (2): 221–5. doi:10.3892/ijmm.10.2.221. PMID 12119563.
  • Lan Y, Kingsley PD, Cho ES, Jiang R (2001). "Osr2, a new mouse gene related to Drosophila odd-skipped, exhibits dynamic expression patterns during craniofacial, limb, and kidney development". Mech. Dev. 107 (1–2): 175–9. doi:10.1016/S0925-4773(01)00457-9. PMID 11520675.

See also

OSR1


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