Neutrophil swarming

Neutrophil swarming is a specific type of neutrophil migration behaviour characterised by a high coordination between neutrophils, clustering of neutrophils to the inflammation site and signalling to other neutrophils further away^[1]. This specific type of migration rely on the production and secretion of LTB4 and on the use of integrins for neutrophil to stop at the cluster site^[2].

References

↑ Tan, Sioh-Yang; Weninger, Wolfgang (February 2017). "Neutrophil migration in inflammation: intercellular signal relay and crosstalk". Current Opinion in Immunology. 44: 34–42. doi:10.1016/j.coi.2016.11.002.
↑ L?mmermann, Tim; Afonso, Philippe V.; Angermann, Bastian R.; Wang, Ji Ming; Kastenm?ller, Wolfgang; Parent, Carole A.; Germain, Ronald N. (26 May 2013). "Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo". Nature. 498 (7454): 371–375. doi:10.1038/nature12175. PMC 3879961.

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[1] Tan, Sioh-Yang; Weninger, Wolfgang (February 2017). "Neutrophil migration in inflammation: intercellular signal relay and crosstalk". Current Opinion in Immunology. 44: 34–42. doi:10.1016/j.coi.2016.11.002.

[2] L?mmermann, Tim; Afonso, Philippe V.; Angermann, Bastian R.; Wang, Ji Ming; Kastenm?ller, Wolfgang; Parent, Carole A.; Germain, Ronald N. (26 May 2013). "Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo". Nature. 498 (7454): 371–375. doi:10.1038/nature12175. PMC 3879961.