NAB1

NAB1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNAB1, NGFI-A binding protein 1
External IDsMGI: 107564 HomoloGene: 4352 GeneCards: NAB1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q32.2Start190,646,746 bp[1]
End190,692,766 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4664

17936

Ensembl

ENSG00000138386

ENSMUSG00000002881

UniProt

Q13506

Q61122

RefSeq (mRNA)

NM_005966
NM_001321312
NM_001321313
NM_001321314
NM_001321315

NM_008667

RefSeq (protein)

NP_001308241
NP_001308242
NP_001308243
NP_001308244
NP_005957

NP_032693

Location (UCSC)Chr 2: 190.65 – 190.69 MbChr 1: 52.46 – 52.5 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

NGFI-A-binding protein 1 is a protein that in humans is encoded by the NAB1 gene.[5][6][7][8]

Interactions

NAB1 has been shown to interact with Zif268.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000138386 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002881 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. 1 2 Russo MW, Sevetson BR, Milbrandt J (Aug 1995). "Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription". Proc Natl Acad Sci U S A. 92 (15): 6873–7. doi:10.1073/pnas.92.15.6873. PMC 41432. PMID 7624335.
  6. ↑ Svaren J, Sevetson BR, Apel ED, Zimonjic DB, Popescu NC, Milbrandt J (Aug 1996). "NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli". Mol Cell Biol. 16 (7): 3545–53. PMC 231349. PMID 8668170.
  7. ↑ Swirnoff AH, Apel ED, Svaren J, Sevetson BR, Zimonjic DB, Popescu NC, Milbrandt J (Jan 1998). "Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain". Mol Cell Biol. 18 (1): 512–24. PMC 115883. PMID 9418898.
  8. ↑ "Entrez Gene: NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)".

Further reading

  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Thiel G, Kaufmann K, Magin A, et al. (2000). "The human transcriptional repressor protein NAB1: expression and biological activity". Biochim. Biophys. Acta. 1493 (3): 289–301. doi:10.1016/s0167-4781(00)00207-4. PMID 11018254.
  • Qiu FH, Devchand PR, Wada K, Serhan CN (2002). "Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils". FASEB J. 15 (14): 2736–8. doi:10.1096/fj.01-0576fje. PMID 11687510.
  • Venken K, Di Maria E, Bellone E, et al. (2003). "Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies". Neurogenetics. 4 (1): 37–41. doi:10.1007/s10048-001-0124-2. PMID 12030330.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.


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