N5-(carboxyethyl)ornithine synthase

N5-(carboxyethyl)ornithine synthase
Identifiers
EC number 1.5.1.24
CAS number 129070-70-8
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a N5-(carboxyethyl)ornithine synthase (EC 1.5.1.24) is an enzyme that catalyzes the chemical reaction

N5-(L-1-carboxyethyl)-L-ornithine + NADP+ + H2O L-ornithine + pyruvate + NADPH + H+

The 3 substrates of this enzyme are N5-(L-1-carboxyethyl)-L-ornithine, NADP+, and H2O, whereas its 4 products are L-ornithine, pyruvate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming). Other names in common use include 5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase, and (L-ornithine-forming).

References

    • Thompson J (1989). "N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase from Streptococcus lactis. Purification and partial characterization". J. Biol. Chem. 264 (16): 9592&ndash, 601. PMID 2498334.
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