Motile sperm domain containing 3

MOSPD3
Identifiers
AliasesMOSPD3, CDS3, NET30, Motile sperm domain containing 3
External IDsMGI: 1916179 HomoloGene: 11406 GeneCards: MOSPD3
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q22.1Start100,612,102 bp[1]
End100,615,384 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

64598

68929

Ensembl

ENSG00000106330

ENSMUSG00000037221

UniProt

O75425

Q8BGG6

RefSeq (mRNA)

NM_001254762
NM_030037

RefSeq (protein)

NP_001241691
NP_084313

Location (UCSC)Chr 7: 100.61 – 100.62 MbChr 5: 137.6 – 137.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Motile sperm domain containing 3 is a protein that in humans is encoded by the MOSPD3 gene.[5]

Function

This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000106330 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037221 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Motile sperm domain containing 3".

Further reading

  • Glöckner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A (October 1998). "Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes". Genome Research. 8 (10): 1060–73. doi:10.1101/gr.8.10.1060. PMC 310788. PMID 9799793.
  • Pall GS, Wallis J, Axton R, Brownstein DG, Gautier P, Buerger K, Mulford C, Mullins JJ, Forrester LM (December 2004). "A novel transmembrane MSP-containing protein that plays a role in right ventricle development". Genomics. 84 (6): 1051–9. doi:10.1016/j.ygeno.2004.08.017. PMID 15533722.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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