Monica Riley

Monica Riley
Born 1926
Died (2013-10-11)October 11, 2013
Richmond, California

Monica Riley (1926 - October 11, 2013) was an American scientist who contributed to the discovery of messenger RNA in her Ph.D work with Arthur Pardee, and was later a pioneer in the exploration and computer representation of the Escherichia coli genome.

After graduating Smith College with a chemistry degree in 1947, she studied Biochemistry at University of California Berkeley with Pardee.[1][2] Her Ph.D. work, together with the PaJaMo experiment, ruled out ribosomes as carriers of information to synthesize protein, leading the discovery of messenger RNA.[3] After holding faculty positions at University of California Davis and SUNY Stony Brook, she moved to the Marine Biological Laboratory in Woods Hole, staying there until age 80.[2] During this time, she helped launch the EcoCyc database of Escherichia coli metabolism[4] and developed classification systems for genes and proteins which were forerunners of gene ontology.[1][2]

References

  1. 1 2 Olena, Abby (November 7, 2013). "Genomics Pioneer Dies". The Scientist.
  2. 1 2 3 Serres, Greta. "Monica Riley (1926 - 2013)".
  3. ↑ Crick , Francis (1988). What Mad Pursuit. pp. 118–119.
  4. ↑ Karp, Peter; Riley, Monica; Paley, Suzanne M.; Pelligrini-Toole, Alida. "EcoCyc: an encyclopedia of Escherichia coli genes and metabolism". Nucleic Acids Research. 24 (1): 32–39. doi:10.1093/nar/24.1.32. PMC 145574. PMID 8594595.


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