Mona Nemer

Mona Nemer
CM CQ FRSC
Dr. Nemer at UBC in 2008
Born c. 1957
Beirut, Lebanon[1]
Occupation Professor
Title Chief Science Advisor of Canada (2017 – present)
Academic background
Alma mater McGill University (PhD)[1]
Witchita State University(BSc)
Academic work
Institutions University of Ottawa
Université de Montréal
Website https://www.uottawa.ca/about/governance/senior-administration/mona-nemer

Mona Nemer, CM CQ FRSC (born c. 1957) is a Lebanese Canadian science professor specializing in cell research. She served as Vice-President Research at the University of Ottawa from 2006-2017. She was formerly a Professor of Pharmacology at the University of Montreal and the Director of the Cardiac Development Research Unit at the Institut de recherches cliniques de Montréal (IRCM) where she held a Tier 1 Canada Research Chair in Cardiovascular Cell Differentiation.[2][3][4] Nemer also served as Director of Academic Affairs and Executive Director of Planning and Development at IRCM.

On September 26, 2017, Prime Minister Justin Trudeau announced that after a selection process, Nemer was chosen as Canada's new Chief Science Advisor.[5][6]

Early Life and Education

Nemer was born in Beirut, Lebanon in 1957 where she found her passion for chemistry.[7] At the age of 17, she and her classmates successfully fought to create a science stream at her all-girls school.[8] She left Lebanon during the civil war[7] and moved to Kansas where she obtained a bachelor's degree in 1977, majoring in chemistry with minors in French and mathematics at Wichita State University.[9] She went on to receive a PhD in bioorganic chemistry from McGill University in 1982.[7][9]

Research career

Nemer's research focuses on the understanding of the molecular mechanisms that register the genetic expression of cardiac cells. She is best known for isolating genes that regulate ventricular hypertrophy which manifests itself in an increase volume of the heart and a thickening of the myocardial wall.[10] Her work has contributed to the development of diagnostic tests for heart failure and the genetics of cardiac birth defects. Nemer has published over 150 scientific research articles to date, and trained over 100 students from Canada and other countries.

Selected Publications

Bruneau, Benoit G.; Nemer, Georges; Schmitt, Joachim P.; Charron, Frédéric; Robitaille, Lynda; Caron, Sophie; Conner, David A.; Gessler, Manfred; Nemer, Mona (2001–09). "A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease". Cell. 106 (6): 709–721. doi:10.1016/s0092-8674(01)00493-7.

Genest, Jacques; McPherson, Ruth; Frohlich, Jiri; Anderson, Todd; Campbell, Norm; Carpentier, André; Couture, Patrick; Dufour, Robert; Fodor, George (2009–10). "2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendations". Canadian Journal of Cardiology. 25 (10): 567–579. doi:10.1016/s0828-282x(09)70715-9.

Durocher, Daniel; Charron, Frédéric; Warren, René; Schwartz, Robert J.; Nemer, Mona (1997-09-15). "The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors". The EMBO Journal. 16 (18): 5687–5696. doi:10.1093/emboj/16.18.5687.

Burns, Kimberly; Duggan, Brenda; Atkinson, Eric A.; Famulski, Konrad S.; Nemer, Mona; Bleackley, R. Chris; Michalak, Marek (1994-02). "Modulation of gene expression by calreticulin binding to the glucocorticoid receptor". Nature. 367 (6462): 476–480. doi:10.1038/367476a0.

Paradis, Pierre; Dali-Youcef, Nassim; Paradis, François W.; Thibault, Gaétan; Nemer, Mona (2000-01-18). "Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling". Proceedings of the National Academy of Sciences. 97 (2): 931–936. doi:10.1073/pnas.97.2.931.

Morin, Steves; Charron, Frédéric; Robitaille, Lynda; Nemer, Mona (2000-05-02). "GATA‐dependent recruitment of MEF2 proteins to target promoters". The EMBO Journal. 19 (9): 2046–2055. doi:10.1093/emboj/19.9.2046.

Drouin, J.; Sun, Y.L.; Chamberland, M.; Gauthier, Y.; De Léan, A.; Nemer, M.; Schmidt, T.J. (1993-01). "Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene". The EMBO Journal. 12 (1): 145–156. doi:10.1002/j.1460-2075.1993.tb05640.x.

Grepin, C.; Nemer, G.; Nemer, M. (1997-06-15). "Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor". Development. 124 (12): 2387–2395.

Sepulveda, Jorge L.; Belaguli, Narashimaswamy; Nigam, Vishal; Chen, Ching-Yi; Nemer, Mona; Schwartz, Robert J. (1998-06-01). "GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression". Molecular and Cellular Biology. 18 (6): 3405–3415. doi:10.1128/MCB.18.6.3405.

Viger, R. S.; Mertineit, C.; Trasler, J. M.; Nemer, M. (1998-07-15). "Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Mullerian inhibiting substance promoter". Development. 125 (14): 2665–2675.

Honours and Awards

References

  1. 1 2 3 "Mona Nemer – Ordre national du Québec". National Order of Quebec (in French). Government of Quebec. Retrieved 28 September 2017.
  2. ↑ "Mona Nemer". UOttawa Awards and Recognition. University of Ottawa. Retrieved August 29, 2014.
  3. ↑ "Dr. Mona Nemer | Molecular Genetics and Cardiac Regeneration Laboratory | University of Ottawa". faculty.uottawa.ca. Retrieved 2017-04-15.
  4. ↑ "$70-million research building opens at U of O". Ottawa Citizen. 2014-09-30. Retrieved 2017-04-15.
  5. ↑ "Government of Canada launches search for Chief Science Advisor". Archived from the original on February 24, 2017. Retrieved 8 December 2016.
  6. 1 2 "Prime Minister introduces Canada's new top scientist" (Press release). Office of the Prime Minister. September 26, 2017.
  7. 1 2 3 Kilpatrick, Sean. "Ottawa researcher Mona Nemer named Canada's new science advisor". The Globe and Mail. Retrieved 22 September 2018.
  8. ↑ "Meet the new voice of science in Canada | The Star". thestar.com. Retrieved 2018-09-22.
  9. 1 2 Proximify. "Members". uniwebtra.uottawa.ca. Retrieved 2018-09-22.
  10. ↑ "Mona Nemer - Google Scholar Citations". scholar.google.ca. Retrieved 2017-04-15.
  11. ↑ "Order of Canada Appointments". June 30, 2014. Retrieved July 1, 2014.
  12. ↑ "Nine Ottawans named to Order of Canada". Ottawa Citizen. 2014-06-30. Retrieved 2017-04-15.
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